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166            PART 2  ■  Hematopoiesis and Cellular Maturation





                      Immature cell                               Mature cell
                                                                                                                              NOTE: This is a good time to review de  nitions of the Key

                                                                                                                              Terms in the Glossary and   ash cards on                                         . It is

                                                                                                                              a good idea to complete Review Questions related to the

                                                                                                                              preceding content.
                                                                                       Decreased overall

                                                                                       cell size

                                                                                                                           NORMAL MA  URA  IONAL

                                                                                                                           CHARAC  ERIS  ICS OF GRANULOCY  ES




                                                                                                                           Myeloblast



                                                                                       Decreased nuclear-                  I         m                     q           (F   .   .  ;             .  ),

                                                                                       cytoplasmic ratio                   m

                                                                                                                           myeloblast (F   .   .  ). T                                                     m-

                                                                                                                                                  µm. T                       m                           -

                                                                                                                               ,                                 -                          . T                 m

                                                                                                                                                m       m                                  m           k

                                                                                                                                       . Auer rods (F   .   .  ),
                                                                                       Increased flexibility
                                                                                       and mobility                                 m   , m                          ,            -  k                           -
                                                                                                                                m                   . T                       m

                                                                                                                                    . A                                      ,            m   ,                .


               FIGURE  8.2  C  m              m                                        . A
               m        ,                           m                                                                      Promyelocyte

               m                                                                    z  ,                                 -

                          m           ,                            x                 m         .                           T   promyelocyte (F   .   .  )                                   m        -
                                                                                                                                                                              . T

                                                                                                                                                                         m                                   m
                              x                 m               m                                                                                                  m                                                 .

               m                                                 m                                                         T                              m        azurophilic

                                               .                                                                                         z  m    m              x         (MPO)

                    T                                                            q

                                           q        z  :       circulating pool                                                      . T         m                                                       ,

               marginating pool. T    m

                                      m                               . S  m

                                                                . M                                                                                                  Myeloblast



                                            . T    m      m                                  m

                                                                                                                                                                     Promyelocyte

                         diapedesis. O                                           ,             -

                      ,                                           ,

                                 phagocytosis.

                    T                                           m                                       -                                                            Neutrophilic myelocyte

                                                                            x m                             .

               O       m                          m                                  ,

                                                                        ,                                     -

                                 ,    x    ,     m                 m .                                                                                               Neutrophilic metamyelocyte

                    E

                                                                                           . B

                                                              m                   .         .

                    I    x                m                                                                                                                          Neutrophilic band

                                   ,     m

                   Charcot-Leyden crystals                                       ,

                             m               .

                    I                           m                                                                                                                    Segmented neutrophil

                     ,                                                                            ,                                                                  (Polymorphonuclear neutrophil)

                               ,         ,                                          . A                                    FIGURE 8.3  N                          . (R                  m A             SA,

                                      m                                     m                                              P           KB. Anderson’s  Atlas  o   Hematology,  P                  , PA:

                                             m                                                              .              L               W      m  & W  k    ,         ,             m        .)
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