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Principles o  Blood Collection and
                                              11                          Classif cation and Laboratory


                  CHAPTER                                                 Assessment
                                                                             Processing o  Anemias


















                            KEY TERMS





               absolute iron de  ciency anem ia                                        functional iron de  ciency anem ia                                      microcytic

               anem ia                                                                 macrocytic                                                              norm ocytic







                            LEARNING OUTCOMES






               Overview  of anemia                                                                                              ■ Give examples of macrocytic anemias and pathological megaloblas-


               ■    Describe the laboratory measurements that de  ne anemia.                                                   tic anemias.


               ■    De  ne the term, functional anemia.                                                                      Referring to the given algorithm, list the laboratory assays that can
               ■    Name underlying disorders that can contribute to anemia.                                                   be used to identify the various categories of anemia.

                                                                                                                           ■    Brie  y explain the characteristics of categories of anemia using a
               Development of anemia                                                                                           pathophysiological basis.



               ■    Explain the relationship of anemia as it relates to normal erythrocyte                                   Compare the morphologic and pathophysiological categories of
                   kinetics                                                                                                    anemia

                 Compare the core problem of absolute iron de  ciency anemia and

                   functional iron de  ciency anemia.                                                                      Laboratory assessment of anemias

                                                                                                                           ■    List the supplementary assays that may be of assistance in estab-
               Clinical signs and symptoms of anemia                                                                           lishing a speci  c anemia diagnosis.


               ■    State what causes the clinical signs and symptoms of anemia.                                             Compare the   ndings of basic tests performed in the hematology

               ■    Brie  y describe the usual complaints of an anemic patient.                                                laboratory to supplementary assays that assist in establishing a dif-

                                                                                                                               ferential anemia diagnosis.
               Classi  cation of anemias


               ■    Describe the organization of anemias according to erythrocyte size                                        NOTE:

                   and explain the limitation of such a system.
                                                                                                                              ■   indicates MLT and MLS core content

                                                                                                                                indicates MLT (optional) and MLS advanced content












               OVERVIEW OF ANEMIA                                                                                          DEVELOPMEN   OF ANEMIA




               A    m                                                                    m                                 T                m          anemia                         m
                                                                    (RBC )                 k                               k          .                              m                     “                 ”


                            m       RBC  (    m         )                             m                                                                  m
                                                                                  ’         ,             ,


                                                        (                           ). F                                                                                         .
                    m                                                                                                           I                      m                                         ,


                                          x                                                                                m         m                                        m                          (    m    -
                       x   .                                                                                                      )                             m    . I                                           m-


                    A    m    m                                                           . U
                                                                                                                                                                                        f            m       z


                     m                                               ,                 x      ,         -                                       m            . D
                            m,        m                     .                                                                       k                                        m   . I                          m













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