Page 288 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

272 PART 4 ■ Erythrocyte Disorders

Glycine
δ-ALA
Porphobilnogen (PBG)
Synthase
Succinyl CoA (4-PBG)
δ-ALA

Hydroxymethylbilane

Heme Heme proteins

Fe 2+

Protoporphyrin IX Uroporphyrinogen III Uroporphyrinogen I Uroporphyrin
(excretion)

Protoporphyrinogen IX Coproporphyrinogen III Coproporphyrinogen I Coproporphyrin

(excretion)

FIGURE 14.8 T m . I m z m x

δ- m k .
(R m M MW, . Green eld’s Surgery Scienti c Principles and Practice, , P ,

PA: L W m & W k , , m .)

P : . S m ,

m , x -
■ C ( . ) . H ,

■ S z m k m m

■ S z m m . W , -

m m .

C , - D m -

m k m . S m m ( C ).

m m . D m

:

m NOTE: This is a good time to complete the nal end of

m . chapter Review Questions.

P m G k , porphyra,

m . T - m ( )

- -

. PBG m x m m CHAP ER HIGHLIGH S

; , m

m , m Iron De ciency Anemia

E ’ . I ■ A ’ m

PBG, m m m

m . . I m (IDA)

W m , m m mm m .

m , m x ■ IDA m m ,

. T - m , m

m , x .

, P B (F . . ). T ■ I m m mm -

sideroblasts. z ,

m ; m ;

DISORDERS RELA ED O HEMOGLOBIN m / m-

BIOSYN HESIS: DISORDERS OF m ; k m;

GLOBULIN SYN HESIS m ,

.

G - ■ N m m , m

. W m , m / . I m x