Page 284 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

268 PART 4 ■ Erythrocyte Disorders

Comparison of Classic Iron

De ciency Anemia Versus
TABLE 14.6
Anemia of In ammation/ Chronic

Disorders

IDA ACD

Serum iron Signi cant Decreased

decrease

TIBC Increased Normal or

decreased

Serum ferritin Decreased Normal to increased

Transferrin Increased Decreased or normal

Soluble transferrin
FIGURE 14.7 P B . I m m -

m ( m Receptor Increased Normal

m). (R m M C (serum sTfR)
KD. Clinical Laboratory Medicine, , P , PA: Transferrin

L W m & W k , , m .)
Saturation Decreased Decreased

Peripheral blood Microcytic Normochromic
m ; . T -

%. RBC morphology Hypochromic Normocytic or micro-
cytic, hypochromic

Clinical Chem istry Studies IDA, iron de ciency anemia, ACD, anemia of chronic diseases or disorders;

A m m m TIBC, total iron-binding capacity.

. S m ( -

) . S m

m m m . T - DISORDERS RELA ED O HEMOGLOBIN
( IBC) m , S BIOSYN HESIS: SIDEROBLAS IC ANEMIA

. I -

- T sideroblastic anemias -

mm . T q z

m mm m . Ex -

m . m - m m mm -

. I . T m m

IBC , IDA m . SF m

. R m - q . S m

mm k . T m m m m -

- m ( ) .

m ACD ( . ). C q

I mm AOI x IDA, - m ( . )

m . I , - . N m m

IDA ACD x . . I m

. M m

Treatment . M q m

m m m . D m

I m , m . I m , m m

k , m ; m

. R m m , SF;

H -EPO (P , ), m - m .

. A AOI m x m . T

, m q m , -

k ( . ., IL- ). m x- k m

C m m . O m

H -EPO m m . x ,