Page 413 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 21 ■ Acute Leukemias 397

. W mm

BOX 21.5 m k m k , k

m , - -

.
Adverse Prognostic Factors

FACTORS USED TO PREDICT A POOR RESPONSE TO Relapse

INDUCTION CHEMOTHERAPY A AML m j m . D -

U k m AML

A > . A m m ,

S AML , ,

Ex , m j m . A

F m , m j

P k > , × /L

.

FACTORS USED TO PREDICT A RELAPSE P — ( ; ),

U k ( ; ), ( ) m — m m

A > x m %

D m q . F

F m m

P k > , × /L - , mm

F m m - ( - ) x m

AML, m k m . m m , -
m HLA-m

HLA-m

Chemotherapy . P q -

m
C x m k m % m . m APL

. m AML m AML.

. L - %

% m m . Allogeneic Hematopoietic-Cell

M AML ALL m ,

x . Transplantation

T : A m m HLA-m

m . T m j m .

m m P m AML m k m -

m . m , x m %

% .

Induction Phase of Therapy P m m -

I m m

m m m -

k m m . mm k m - - -

C - k m . A m -

m m . A m k x

% % m m

. I , m- .

% %.

I AML m Transplantation Techniques

( , A -C) C m

( ). P k m f mm

AML m m , m m . N m -

(HIDAC) m f mm

m m , m x , . j . A

O m , m m m

AML . m ,

m x m . F
Consolidation Therapy m k

S m m

m m mm . k