Page 415 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 21 ■ Acute Leukemias 399

TABLE 21.15 Morphological Classi cation and Characteristics of ALL

FAB Type Morphological Classi cation and Characteristics

Size of Blasts Nuclear Shape Nucleoli Cytoplasm

L1 Small Indistinct Scant Invisible

L2 Large, heterogeneous Indented, prominent Large, abundant Moderately clefted

L3 Large Regular oval to round Prominent, basophilic Prominent, vacuoles

ALL, acute lymphocytic leukemia; FAB, French-American-British Cooperative Group Classi cation.

E V k m ALL. A m m P x m m

ALL k m k , m . G m

x m . m mm . L m

m % . L k m m -

Classi cations of Acute Lymphoblastic

Leukemia k m q mm . L k m

m (F . . ). N
T FAB ALL m

■ L ( ) k .

■ L ( )

■ L ( k m B k ’ Laboratory Data

m m ) I ALL, m m m m –

T m - m . T -

, z , m , k % % ,

m m ( . ). A k m × /L. L
- % x m k k -

m . ALL m × /L. I x m
k m m % k .

m m . P m (F . . ) m -

ALL m - B- . I % . I

- m k m ( -ALL) , m

m m m m - % m , m , m . T

m , - m . m , A

I , m % ALL L . m m. T

-ALL % ALL .

-ALL % % ALL. T

m ALL B m .

T WHO m FAB

L L B m k -

m / m m m ( B- ALL)

m k m / m m-

m ( - ALL), . P B-

m k m (B-ALL) m m-

mm B- . P -ALL

m m mm - .

Clinical Signs and Symptoms

T m m ALL m

k . S m m , , -

, , , m . B j FIGURE 21.16 L k m

m m m m ALL. (R m m W, J E. Te Wills Eye

mm . P x m , , Hospital Atlas o Clinical Ophthalmology, , P , PA:

k m . L W m & W k , , m .)