Page 417 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 21 ■ Acute Leukemias 401

m , m m - DNA. (+)

. m m

m j ALL - B- ,

Special Identi cation Techniques x m B- ALL,

m m AML. -
S m k , m m m m m m

mm , x m CML . I -

ALL (F . . ). D - , m k

x m , m .

m m k T mm ALL ( ALLA) -

m ( . ). m x - m % ALL. CD

( ) z m z
x

ALL.

Cytogenetic Analysis in Acute

Lymphoblastic Leukemia

A m k m

m k . S ALL

( ; ), ( ; ), ( ; ), ( ; ), ( ; ), P m -

m . G m m m m

, , . A m k-

L L ALL,

( ; ) mm L ALL

B k ’ m m m m -

m m .

P m m m k -

m ; m

k m m ,

( ; ), ( ; ), ( ; ) .

Treatment

T m m m ALL

m x m

m

m . R ,

-m x . m

m P (P ) m m

ALL. P m m m m

m m . G ,

m m m BCR

m m m j x -

m k m ABL m m m

. A P m m

CML, x m % % ALL

m P m m .

F - - ABL k

m - P m m -

ALL. I m m , -

- k , -C x
FIGURE 21.20 A m , m , m -

k m : m . MPO, m x ; SBB, ( m ), , m ( x ),
S k B; PAS, -S ; ANAE, - x m ( -CVAD) m ALL

( ); N F, m ( ; ) m m m

; CAE, . (R m R E, m m m .
F JL. Pathology, , P , PA: L W m Imm , m m ,

& W k , , m .) m m z