Page 667 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )
P. 667

CHAPTER 30  ■  Instrumentation in Hematology                             651







                                 REVIEW QUESTIONS (continued)





                        16.  Te RDW and MCV are both quantitative descrip-                                                       24.  Te MPV is o  en decreased

                             tors o  erythrocyte size. I  both are increased, the most                                                 A.  in sickle cell anemia

                             probable erythrocytic abnormality would be                                                                B.  in megaloblastic anemia

                             A.  iron de  ciency anemia                                                                                C.  in idiopathic thrombocytopenic purpura

                             B.  acquired aplastic anemia                                                                              D.  a  er splenectomy

                             C.  megaloblastic anemia

                             D.  hemoglobinopathy                                                                                25.  A normal PDW is

                                                                                                                                       A.  less than 5%
                      *17.  I  the RBC distribution on a histogram demonstrates                                                        B.  less than 10%

                             a homogeneous pattern and a small SD, the peripheral                                                      C.  less than 15%

                             blood smear would probably exhibit                                                                        D.  less than 20%

                             A.  extreme anisocytosis

                             B.  very little anisocytosis                                                                        26.  Which o  the  ollowing can be an application o  f ow-

                             C.  a single population o  spherocytes                                                                    cell cytometry?

                             D.  a single population o  macrocytes                                                                     A.  Screening erythrocytes  or malaria


                                                                                                                                       B.  Counting o  reticulocytes
                        18.  Te                 can be determined  rom a WBC histogram.                                                C.  Quantitation o     and B cells

                             A.  percent o  lymphocytes                                                                                D.  All o  the above

                             B.  absolute number o  lymphocytes

                             C.   requency distribution o  granulocytes                                                          27.  Major systems in a f ow cytometer include all o  the

                             D.  all o  the above                                                                                       ollowing except


                                                                                                                                       A.  fuidics
                        19 and 20.  Te sorting o  leukocyte subpopulations in the                                                      B.  optics

                        WBC histogram determined by electrical impedance ref ects                                                      C.  computerized electronics

                        the (19)               , which is primarily related to their (20)                              .
                                                                                                                                       D.  gating



                        19.                                                                                                    *28.  T e restriction o  data analysis to one cell population
                             A.  overall size                                                                                          is accomplished by

                             B.  relative size                                                                                         A.  ampli  cation

                             C.  nuclear size

                             D.  chromatin pattern                                                                                     B.  gating
                                                                                                                                       C.  compensatory monitoring


                        20.                                                                                                            D.  data limitation

                             A.  cytoplasmic size
                             B.  nuclear size                                                                                    29.  Which cell sur ace membrane marker is used  or enu-


                             C.  concentration o  granules                                                                             meration o  HPC enumeration?
                             D.  cytoplasmic color                                                                                     A.  CD4

                                                                                                                                       B.  CD8

                        21.  T e mononuclear cells in a WBC histogram can include                                                      C.  CD34

                             A.  blast cells                                                                                           D.  CD45

                             B.  promyelocytes

                             C.  monocytes                                                                                       30.  Reticulocytes can be detected by using                                       stain.

                             D.  all o  the above                                                                                      A.  new methylene blue

                                                                                                                                       B.  thiazole orange
                      *22.  A combined scatter histogram measures                                                                      C.  propidium iodide

                             A.  overall size versus nuclear size                                                                      D.  both A and B

                             B.  cytoplasm-to-nucleus ratio

                             C.  cell size and granularity                                                                       31.  Te newer clinical instruments  or measuring blood

                             D.  cell shape and cytoplasmic color                                                                      clotting are based on


                                                                                                                                       A.  clot elasticity
                        23.  Te MPV is                                                                                                 B.   brin adhesion

                             A.  analogous to the MCHC                                                                                 C.  conduction o  impedance o  an electrical current by

                             B.  a direct measure o  the platelet count                                                                      brin

                             C.  a measurement o  the average volume o  platelets

                             D.  a comparison o  the patient’s value to the normal value                                               D.  changes in optical density




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