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CHAPTER 30  ■  Instrumentation in Hematology                             647







                                 CASE STUDIES (continued)
                                  CASE STUDIES (continued)





                        Case Study 30.9                                                                                         ■    Absolute Cell Counts



                     ■    History and Physical                                                                                                                                       Patient               Reference

                     K.C., a 70-year-old nurse, su  ered  rom degenerative arthri-                                                                               Units               Value                 Range

                     tis. She visited her rheumatologist because o  increasing pain                                                 Neutrophils                  10 /µL              13                    2.0–8.0
                                                                                                                                                                     3
                     in her knees.
                                                                                                                                                                     3
                     A  CBC  and  erythrocyte  sedimentation  rate  (ESR)  were                                                     Lymphocytes                  10 /µL              1.44                  1.0–5.0

                     ordered. Synovial f uid was removed  rom one knee  or                                                          Monocytes                    10 /µL              3.6                   0.1–1.0
                                                                                                                                                                     3
                     examination.

                                                                                                                                ■    Critical Thinking Group Discussion Questions
                     ■    Laboratory Data
                                                                                                                                1.  Are any o  the laboratory values abnormal?

                         Measurement                    Units                      Reference Range*

                                                                                                                                2.  Why are the absolute cell counts important data?
                         RBC                            3.41 × 10 /µL              4.00–6.20
                                                                      6

                         Hgb                            11.0 g/dL                  11.0–18.8                                    3.  Should additional laboratory assays be ordered?


                         Hct                            31%                        35.0–55.0
                                                                                                                                    Case Study 30.10
                                                                   3
                         WBC                            18 × 10 /µL                6.0–11.0

                         PLT                            210 × 10 /µL               150.0–400.0                                  ■    History and Physical
                                                                     3
                                                                                                                                M  , a 45-year-old white  emale, began to experience abdom-
                         MCV                            92 fL                      80.0–100.0                                   inal pain over the last several days. She went to a primary


                         MCH                            32 pg                      26.0–34.0                                    care clinic  or help.

                         MCHC                           35 g/dL                    31.0–35.0                                    A CBC was ordered.


                         RDW                            12%                        10.0–20.0
                                                                                                                                    Measurement                    Units                      Reference Range*
                         MPV                            9 fL                       6.0–10.0

                                                                                                                                                                               6
                         fL, femtoliters; pg, pictogram.                                                                            RBC                            5.1 × 10 /µL               4.00–6.20

                         *Published for Beckman Coulter A  T .                                                                      Hgb                            13.0 g/dL                  11.0–18.8

                                                                     C TM
                                                                                                                                    Hct                            37%                        35.0–55.0


                                                                                                                                    WBC                            23.0 × 10 /µL              6.0–11.0
                                                                                                                                                                                 3
                                                                                                                                                                                3
                         Leukocyte Differential                                                              %                      PLT                            450 × 10 /µL               150.0–400.0

                                                                                                                                    MCV                            72 fL                      80.0–100.0
                         Band neutrophils                                                                       5

                                                                                                                                    MCH                            25 pg                      26.0–34.0
                         Polymorphonuclear segmented neutrophils (PMNs)                                       65
                                                                                                                                    MCHC                           35 g/dL                    31.0–35.0
                         Lymphocytes                                                                            8
                                                                                                                                    RDW                            17%                        10.0–20.0
                         Monocytes                                                                            20
                                                                                                                                    MPV                            8.0 fL                     6.0–10.0
                         Eosinophils                                                                            1
                                                                                                                                    fL, femtoliters; pg, pictogram.
                         Basophils                                                                              1

                                                                                                                                    * Published for Beckman Coulter A  T .
                                                                                                                                                                                C TM
                         Total                                                                              100






                                                   VOL                                                         RBC                                         PLI













                                                                                                                                WBC/
                                                                                                                                BASO









                                                                                                  ABS




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