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CHAPTER 14  NUCLEAR AND CYTOPLASMIC CHANGES IN LEUKOCYTES  139

                                                  DÖHLE BODY






















                  A                                          B
                        FIGURE 14–4A  Döhle body.                  FIGURE 14–4B  Döhle body


                     DESCRIPTION:  Gray-blue, variably shaped
                     LOCATION:  Cytoplasm
                     COMPOSITION:  Ribosomal RNA
                     NUMBER:  Single or multiple
                     Associated with:  Wide range of conditions, including bacterial infection, sepsis and normal
                       pregnancy
                     NOTE:  May be seen in cells with toxic granulation or on same slide with toxic granulation.
                       (see Figure 14-5, B)
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