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CHAPTER 14 NUCLEAR AND CYTOPLASMIC CHANGES IN LEUKOCYTES 141
HYPOGRANULATION/AGRANULATION
A B
FIGURE 14–6A Hypogranulation. FIGURE 14–6B Agranulation.
DESCRIPTION: Decreased number or absence of
specific granules giving the cytoplasm a colorless
appearance
Associated with: Myelodysplastic syndrome,
myeloproliferative neoplasms, infection
C
FIGURE 14–6C Normal segmented neutrophil for
comparison.
