Page 158 - Clinical Hematology Atlas

142 SECTION FOUR LEUKOCYTES

REACTIVE LYMPHOCYTES

A B C
FIGURE 14–7A Reactive lympho- FIGURE 14–7B Reactive lympho- FIGURE 14–7C Reactive lympho-
cyte, vacuolated cytoplasm. cyte, peripheral basophilia. cyte, cytoplasm indented by
adjacent cells.

D E
FIGURE 14–7D Reactive lymphocyte, radial FIGURE 14–7E Reactive lymphocytes, characteristic
basophilia. of viral diseases, such as infectious mononucleosis
(PB 3500).

SHAPE: Pleomorphic; easily indented by surrounding cells
SIZE: 10-30 mm
NUCLEUS: Irregular
Nucleoli: Occasionally present
Chromatin: When compared with that of a resting lymphocyte, chromatin coarse to fine and
dispersed.
CYTOPLASM: Pale blue to deeply basophilic, may stain unevenly with peripheral or radial
basophilia
Granules: May have increased numbers of azurophilic granules
Vacuoles: Occasional
Associated with: Viral infections and other antigenic stimulation, including organ transplantation