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CHAPTER 22 MISCELLANEOUS CELLS 211
D
FIGURE 22-1D Alder-Reilly anomaly (PB 31000). (Courtesy Dennis P. O’Malley, MD,
Clarient, Inc., Aliso Viejo, CA.)
DESCRIPTION: Deep purple to lilac granules difficult to distinguish from toxic granulation;
occur in neutrophils and occasionally eosinophils and basophils
E
FIGURE 22–1E May-Hegglin Anomaly. Note Döhle-like body at arrow (PB 31000).
DESCRIPTION: Characterized by thrombocytopenia with large platelets and large basophilic
inclusions resembling Döhle bodies in granulocytes and monocytes with the absence of toxic
granulation
NOTE: These inclusions are sporadically visible by light microscopy but always detectable by
electron microscopy. The ultrastructure varies from that of Döhle bodies.
