Page 231 - Clinical Hematology Atlas
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CHAPTER 22 MISCELLANEOUS CELLS 215
A B
FIGURE 22–4A Metastatic tumor (BM 3100). FIGURE 22–4B Metastatic tumor (BM 3500).
DESCRIPTION: Tumor cell clusters may be recognized during the 3100 scan of bone marrow,
especially at or near the edge of the coverslip or glass slide. Characteristics of the tumor cells
are more easily observed at 31000 magnification. Cells are variable in size and shape within
the same tumor clump. Nuclei vary in size and staining characteristics. Nucleoli are usually visi-
ble. It is sometimes difficult to distinguish one cell from another because of “molding” of cells.
A B
FIGURE 22–5A Sea blue histiocyte (BM 31000). FIGURE 22–5B Erythrophagocytosis (BM 31000).
DESCRIPTION: Macrophage 20 to 60 mm in DESCRIPTION: Monocyte or macrophage with
diameter with eccentric nucleus; cytoplasm engulfed erythrocyte; may be seen in some
contains varying numbers of prominent blue-green transfusion reactions
granules; may be seen in diseases with rapid cell
turnover, such as myeloproliferative neoplasms
