Page 230 - Clinical Hematology Atlas

214 SECTION FIVE MISCELLANEOUS

A
FIGURE 22–3A Endothelial cells lining a blood B
vessel (BM original magnification 3500). FIGURE 22–3B Endothelial cells (BM original
magnification 31000).

DESCRIPTION: Large, elongated cells, 20 to 30 mm; one oval nucleus with dense chromatin;
nucleoli not visible; function is to line blood vessels; may also be seen in peripheral blood

C D
FIGURE 22–3C Osteoblasts (BM original FIGURE 22–3D Osteoclast (BM original
magnification 31000). magnification 31000).

OSTEOBLAST OSTEOCLAST
SIZE: 30 mm SIZE: Very large, .100 mm
DESCRIPTION: Comet or tadpole shaped; single, DESCRIPTION: Multinucleated with irregularly
round, eccentrically placed nucleus, may be shaped ruffled border; nuclei are round to oval,
partially extruded; abundant cytoplasm with separate and distinct with little variation in nuclear
chromophobic area located away from nucleus; size; cytoplasm may vary from slightly basophilic to
often appear in groups; function in synthesis of very acidophilic; coarse granules may be present;
bone osteoclasts function in the resorption of bone
NOTE: May be confused with plasma cells. NOTE: May be confused with megakaryocytes.