Page 290 - Review of Medical Microbiology and Immunology ( PDFDrive )
P. 290
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mebooksfree.com mebooksfree.com mebooksfree.com ANSWERS CHAPTER 35 Antiviral Drugs 279 mebooksfree.com
(D) Inhibits viral protein synthesis by binding to the 60S ribosomal
subunit
1. (D)
(E) Inhibits the neuraminidase required for release of virus from
2. (E)
the infected cell
3. (D)
3. Which one of the following is a well-described adverse effect of the
4. (E)
protease inhibitors used in the treatment of HIV infection?
(A) Bone marrow suppression
(B) Central nervous system disturbances
(C) Drug-induced hepatitis
COURSE EXAMINATIONS
(D) Lipodystrophy PRACTICE QUESTIONS: USMLE &
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(E) Peripheral neuropathy
Questions on the topics discussed in this chapter can be found
4. Regarding acyclovir, which one of the following is the MOST
in the Basic Virology section of Part XIII: USMLE (National
accurate?
(A) Bone marrow suppression is a significant adverse effect.
XIV: USMLE (National Board) Practice Examination starting
(B) It terminates the latent state of both herpes simplex virus type
on page 751.
1 and type 2.
(C) It inhibits the virus-encoded thymidine kinase that is required
to synthesize viral DNA.
(D) Resistance to acyclovir is primarily caused by proton pumps
that export the drug from the cell.
(E) It is a chain-terminating drug because it does not have a com-
plete ribose ring and therefore lacks a hydroxyl group in the
correct position.
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