Page 10 - COPD - Training Manual - Module 4

Figure 22: Results of device-handling study and ease-of-use
questionnaire (n=459)

The study concluded that Synchrobreathe® inhaler usage is easier to learn and
teach, with reduced device handling errors compared with a pMDI. Overall,
Synchrobreathe® was the preferred device and enjoyed a higher level of patient
satisfaction.

Key Takeaways:

Synchrobreathe® is a compact, robust and portable inhaler with a dose
counter, and it is easy to use and is breath-actuated.

It consists of multiple internal parts that work in synchronisation to deliver
standard, uniform doses with every inhalation.

Synchrobreathe® can be used with just three simple steps: shake and
open, breathe, and close the inhaler. Cleaning the Synchrobreathe® inhaler
is also very easy, making it a hassle-free device.

The lung deposition of inhaled drug with Synchrobreathe® is greater than
that achieved by the pMDI as confirmed by in vitro and in vivo
(gamma-scintigraphy) studies.

In a device-handling study carried out with Synchrobreathe® in healthy
volunteers, asthma and COPD patients, the conclusion was that
Synchrobreathe® is an easy-to-use device, with less chances of errors in
usage, and requires lesser training time compared with pMDIs and is also
preferred by patients.
Synchrobreathe® inhaler is designed to be triggered with a very low
inspiratory flow rate ranging from approximately 23 to 35 L/minute,
indicating that the device can be used by patients with very severe COPD
as well those who have lower inspiratory capacity.