Page 9 - Livestock Production E Magazine-893
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INTRADERMAL APPLICATION

        OF VACCINES IN PIGS





            Mechanism of action













      EPIDERMIS



      DERMIS                      Inflamatory
                                  Dendritic Cell (DC)
                                  Blood vessel
                                  Resident DC taking
     ADIPOSE  TISSUE (S.C.)       up antigen
                                  Lymph vessel with DC
                                  migrating to lymph node

        The dermis represents an excellent
        site for vaccine delivery being rich in
        resident DC, lymph vessels and
        blood capillaries.

      1                                        2                                       3

                      90º



                  Pig skin                                Pig skin                                Pig skin
     As a needle-free injector, Hipradermic ®1  injector head must contact the surface of the pig's skin at a 90º angle. Hipradremic ®  has no trigger, so it
     is enough to make a small movement towards the animal to carry out the vaccination.

         Adequate regions for intradermal           Correct administration          Comparison between intradermal (ID)
           administration of vaccines                  of the vaccine                 and intramuscular (IM) application










                                                                                             1  2  3  4  5  6  7  8
     Sows              Sows                Papule in sows                         In the ID application the vaccine is deposited
                                           Observed in 90% of the sows vaccinated with   at the dermal layer of the skin (before the
                                                   ®2
                                           Hipradermic .                          subcutaneous fat).










     Sows              Piglets             Injection point in piglets             For IM application is very important to select
                                           In piglets no papule is observed, just an   the adequate needle length tacking into
                                           injection point can be seen.           account the subcutaneous fat.
      (1) Hipradermic ®, needle-free device with full traceability
       for the vaccination of sows and piglets.
      (2) Busquet et al., 2017. ESPHM Proceedings.
                                                        www.hipra.com
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