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Obstructive Sleep Apnoea (OSA): Cardiodiabetic issues 189

Treatment 2009:136:1668-77
The most effective treatment for OSA is weight re- 16. Loeppky JA, Voyles WF et al Sleep apnea and autonomic cerebrovascular
duction, with a loss of 10.7kg resulting in a 40% drop dysfunction. Sleep 1987:10:25-34
19
in the AHI/strangulation score , in the mild severity. 17. Tuomilehto HP, Seppa J et al Lifestyle intervention with weight reduction:
Lifestyle changes in those with moderate and severe first line treatment in mild obstructive sleep apnoea
OSA is much more difficult as they patients are gen- 18. Pepperell J, Ramdassingh-Dow S et al Ambulatory blood pressure after
erally very fatigued and are unable to comply with therapeutic and sub-therapeutic nasal continuous positive airway pressure
physical activity regimes. for obstructive sleep apnea: a randomized parallel trial. Lancet 2002:
359:204-10
CPAP (continuous positive airway pressure) is, for 19. Babu AR, Herdegen J et al Type 2 diabetes, glycaemic control and con-
most patients, the treatment of choice due both to its tinuous positive airway pressure in obstructive sleep apnoea. Arch Intern
effectiveness in reducing the subjective symptoms Med 165(4):447-453: 2005
e.g. fatigue and tiredness but also the complications
of the diseases as discussed. Improved blood pres-
sure, better control and reduction of HBA1c and
21
heart failure .
22
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