Page 128 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003
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A.  Measurement of dead space
                                                                       Dead Space, Residual Volume, Airway Resist.
                             Alveolar part
                               of tidal                      Tidal
                              volume Dead space  Mixing     volume
                                VA   volume                   VT
                                      VD
                               FA CO 2  FI CO 2              FE CO 2

                                                         CO 2  volume
                                      Dead space
                           Alveolar CO 2  +       =
                            volume   CO 2  volume        in expired air
                                                  =
                             VA · FA CO 2 + VD·FI CO 2     VT · FE CO 2


                             VA =VT–VD  FI CO 2 =0        Insert values

          Bohr equation              Using normal values:
                                   )              VD  =  0.5   (0.056 – 0.040)  Plate 5.5
                         VT   (FA CO 2  – FE CO 2
             Dead space VD  =                           0.056
                                           Dead space VD  = 143 mL
                             FA CO 2
         B.  Measurement of residual volume and functional residual capacity




               VSp



                      FHe 0                                  FHe X



                                  Mixing
               VL


             Helium volume                           Helium volumen
           (in spirometer only)   =                   (in lung and
                                                      spirometer)
                                  =
             VSp · FHe 0                            (VSp+VL)·FHe X

                                   .  FHe 0 –FHe X  VSp   and FHe 0  are known
                              VL  = VSp
                                      FHe X   FHe X :  Measurement   115
       Despopoulos, Color Atlas of Physiology © 2003 Thieme
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