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A.  Anatomy of the stomach             B.  Gastric filling
        Esophagus      “Proximal” stomach       Filling  50 mL  250 mL  500 mL  max.
        Cardia                        Gastric juice              ca. 1500 mL
        Fundus                  Mucus
        Corpus
        Antrum                          Mucous
        Pylorus                         neck cell
        Duodenum                                                       and Motility
                                       Parietal cell

               “Distal stomach”         Chief cell
                                                          (After Code et al.)
         C.  Motility cycle of distal stomach                          Stomach Structure
               Duodenal cap
                             Liquid
        Duodenum
        Pyloric
        canal                   Solid
        Antrum                                                         Plate 10.8
                1        2       3        4       5        6
                Cineradiography images                  (After Carlson et al.)
         D.  Factors that influence gastric motility

               Hypoglycemia,       CNS
           psychological factors,                Pain,
               taste, smell, etc                 psychological factors, etc.
                          Sympathetic     Vagal
                             nerves       nerve  Adrenergic
                                               Cholinergic
                                                 VIP, etc.
            CNS and           Pace-        Receptive
            prevertebral      maker        relaxation
            ganglia           zone
             Adrenergic       Cholinergic

          Enterogastric reflex         Pylorus   Free  H  ions

                                          Narrow
                                                 amino
                                                 acids
                                                        +
                           Peristaltic
                                                       Osmolality
                           waves           Dilated     Fatty acids
                                                       Tryptophan
        Stretching
                    SIH                            Gastrin
                                          SIH
              GIP, etc.  Gastrin              Motilin
                                       CCK, GIP
           1  Distal stomach           Secretin                       241
               (mixing and processing)  2  Proximal stomach and pylorus (emptying)
       Despopoulos, Color Atlas of Physiology © 2003 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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