Page 403 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003
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-1
          U osm = osmolality of urine [Osm · L ]  b. Elliptical hollow body, considering wall
          P X, P PAH, P In = plasma concentration of sub-  thickness:
          stance X, para-aminohippuric acid, and in-  1  1
          dicator (e.g., inulin, endogenous crea-  P tm = S · w (  r 1  +  r 2  ) [Pa];
                   -1
                         -1
          tinine) [mol · L ] or [g · L ]  c. Spherical hollow body (r 1 = r 2 = r):
                               -1
          P osm = osmolality of plasma [Osm · L ]  T      S · w
          HCT = hematocrit [L of blood cells/L of  P tm = 2  r  [Pa] or P tm = 2  r  [Pa];
          blood]
                                        d. Cylindrical hollow body
       9. Equations for filtration        (r 2 ! ', therefore 1/r 2 = 0):
         (see also pp. 152, 208)          P tm =  T  [Pa] or P tm =  S · w  [Pa]
         a. Effective filtration pressure at capillaries  r  r
          (P eff)                         P tm = transmural pressure [Pa]
          P eff = P cap –P int – π cap + π int [mmHg]  T = wall tension [N · m ]
                                                       -1
                                                       -2
                                          S = wall tension [N · m ]
         b. Effective filtration pressure at capillaries  w = wall thickness [m]
          of renal glomerulus:
          P eff = P cap –P Bow – π cap [mmHg]  11. Equations for cardiovascular function
    Appendix  c. Filtration rate (Q at glomerulus = GFR)  (see also items 2, 5b, 6c, and 9 as well as
                    .
           .
          Q = P eff · F · k [m · s
                        ]
                       –1
                    3
                                        p. 186ff.)
                                        a. Cardiac output (CO):
                                                     –1
       (interstitium) [mm Hg]
    13  P cap (P int) = hydrostatic pressure in capillaries  CO = f · SV [l · min ]
       π cap (π int) = oncotic pressure in capillaries  b. Hagen–Poiseuille equation
       (interstitium) [mm Hg]                8 · l · η
       P eff = mean effective filtration pressure [mm Hg]  R =  π · r 4  ;
                     2
       A = area of filtration (m )        f = heart rate [min ]
                                                     -1
       k = permeability to water (hydraulic conduc-  SV = stroke volume [L]
              -1
             3
                    -1
       tance) [m · s · mm Hg ]            R = flow resistance in a tube [Pa · s · m ] of
                                                                -3
                                          known length l [m] and inner radius r [m]
       10. Law of Laplace                 η = viscosity [Pa · s]
         (see also pp. 118, 188, and 210)
         a. Elliptical hollow body (with radii r 1 and r 2)
                1   1
          P tm = T (  +  ) [Pa];
                r 1  r 2


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