Page 64 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. Chemical synapse

Na + AP 1 0 0 2
Presynaptic
action potential
mV

–80
Calmodulin
Presynaptic
Ca 2+ ending 3
2+
Ca 2+ Ca influx 0 Synaptic Transmission I
nA I Ca
Vesicle –0.5
CaM-
kinase II
Synapto-
tagmin
Active zone
Transmitter 4
Transmitter Plate 2.5
in cleft
Ionotropic Synaptic Transmitter
receptor or cleft release mmol/L 1
Metabotropic 0
receptor Cation
channel
Postsynaptic cell
(Partly after Llinás)
5
Synapsin
CaM-
kinase II
Vesicle
preparation
Active zone
Docking
mV
Transmitter binding 0
K + to receptors
or
Na + (Ca )
2+
EPSP 1 EPSP 2 EPSP 3
Signal chain K +
6
2+
+
7 Ca (Na ) Summation
Postsynaptic –90 51
action potential (see plate B.)
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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