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CHAPTER 80: Viral Hemorrhagic Fevers  735



                      TABLE 80-1    Etiology and Epidemiology of Viral Hemorrhagic Fevers (Continued)
                                Pathogens
                                                                Geographic
                    Family   Genus    Virus         Disease     Distribution  Common Modes of Human Infection  Reservoir
                                      Junin virus (JUNV)  Argentine HF  Argentina  Aerosol of urine or direct contact   Vesper mice (Calomys musculinus
                                                                              with rodent            and C laucha)
                                      Machupo virus (MACV)  Bolivian HF  Bolivia  Aerosol of urine or direct contact   Vesper mouse (Calomys callosus)
                                                                              with rodent
                                      Guanarito virus (GTOV) Venezuelan HF  Venezuela  Aerosol of urine or direct contact   Short-tailed cane mouse (Zygodontomys
                                                                              with rodent            brevicauda)
                                  https://kat.cr/user/tahir99/
                                      Chapare virus   Chapare HF  Bolivia     Unknown                Unknown
                                      Sabiá virus (SABV)  Brazilian HF  Brazil  Unknown initial case; lab infections  Unknown
                    Filoviridae  Marburgvirus Lake Victoria   Marburg HF  Africa  Infection in caves or mines infested by   Most likely Egyptian fruit bat (Rousettus
                                        marburgvirus (MARV)                   bats; person-to-person transmission  aegyptiacus)
                             Ebolavirus  Zaire (ZEBOV)  Ebola HF  Africa      Probable exposure to tree-dwelling    Probably tree-dwelling African fruit bats
                                                                              African fruit bats; person-to-person
                                                                              transmission
                                      Sudan (SEBOV)
                                      Côte d’Ivoire (CIEBOV)
                                      Bundibugyo (BEBOV)
                                      Reston (REBOV)  Nonpathogenic  Philippines  Handlers of monkeys and pigs  Probably pigs
                    Bunyaviridae Nairovirus  Crimean-Congo   Crimean-Congo HF Africa, Europe, and   Tick bite; exposure to livestock;    Ticks (Hyalomma marginatum)
                                      HF virus (CCHFV)          Asia          person-to-person transmission
                             Phlebovirus  Rift Valley fever virus   Rift Valley fever  Africa  Mosquito bites; exposure to sheep and   Flood mosquitoes (Aedes mcintoshii)
                                      (RVFV)                                  cattle; lab infections
                                                                Arabian Peninsula
                                      Severe fever with   Severe fever with   China  Tick bite; person-to-person transmission Ticks (Haemaphysalis longicornis)
                                      thrombocytopenia   thrombocytopenia
                                      syndrome virus  syndrome (SFTS)
                             Hantavirus   Hantaan virus (HTNV)  HFRS (Korean HF)  China, South Korea,   Mostly primary aerosols of rodent urine,  Korean striped field mouse (Apodemus
                             (HFRS group)                       Russia        with low risk of secondary aerosols from  agrarius koreae)
                                                                              urine, feces, and respiratory secretions
                                      Amur virus (AMRV)  HFRS   China, South Korea,   Like Hantaan virus  Apodemus peninsulae
                                                                Russia
                                      Dobrava-Belgrade   HFRS   Balkans       Like Hantaan virus      Yellow-necked forest mouse (Apodemus
                                      virus (DOBV)                                                    flavicollis)
                                      Saaremaa virus  HFRS      Baltic countries and   Like Hantaan virus  Apodemus agrarius
                                                                eastern Europe
                                      Puumala virus (PUUV)  HFRS (NE)  Europe  Like Hantaan virus     Myodes glareolus
                                      Seoul virus   HFRS        Worldwide in cities  Like Hantaan virus  Norwegian rat (Rattus norvegicus)
                             Hantavirus   Sin Nombre virus (SNV) HCPS  North America  Primary aerosols of rodent urine; low   Deer mouse (Peromyscus maniculatus)
                             (HCPS group)                                     risk of secondary aerosols from urine,
                                                                              feces, and respiratory secretions
                                      New York virus (NYV)  HCPS  North America  Like Sin Nombre virus  White-footed mouse (Peromyscus leucopus)
                                      Monongahela   HCPS        North America  Like Sin Nombre virus  Deer mice (Peromyscus maniculatus)
                                      virus (MGLV)
                                      Black Creek Canal                       Like Sin Nombre virus   Cotton rat (Sigmodon hispidus)
                                      virus (BCCV)
                                      Bayou virus (BAYV)                      Like Sin Nombre virus   Rice rat (Oryzomys palustris)
                                      Andes virus (ANDV)  HCPS with DIC  South America  Like Sin Nombre virus plus person-to-  Oligoryzomys longicaudatus
                                                                              person transmission
                                      Araraquara, Juquitiba,   HCPS  South America  Like Sin Nombre virus  Various rodents
                                      Laguna Negra, Choclo,
                                      Bermejo, Lechiguanas,
                                      Maciel, Oran virus
                    DHF, dengue hemorrhagic fever; DIC: disseminated intravascular coagulation; DSS, dengue shock syndrome; HCPS, hantavirus cardiopulmonary syndrome; HF, hemorrhagic fever; HFRS, hemorrhagic fever with renal
                    syndrome; NE: nephropathia epidemica.








            section05_c74-81.indd   735                                                                                1/23/2015   12:37:42 PM
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