Page 258 - Clinical Application of Mechanical Ventilation
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224    Chapter 8



                        TABLE 8-8 Determination of Circuit Compressible Volume

                        	 1.	 	With	the	circuit	warmed	to	an	operating	temperature,	set	the	frequency	at	10	to	16/min
                            and	the	tidal	volume	between	100	and	200	mL	with	minimal	flow	rate	and	maximum	high
                            pressure	limit.
                        	 2.	 	Completely	occlude	the	patient	Y-connection	of	the	ventilator	circuit.

                        	 3.	 	Record	the	expired	volume	(mL)	and	the	peak	inspiratory	pressure	during
                            Y	occlusion	(cm	H O).
                                            2
                        	 4.	 	Divide	the	expired	volume	(mL)	by	the	peak	inspiratory	pressure	during	Y	occlusion(cm	H O);
                                                                                                             2
                            this	is	the	circuit	compression	factor.
                        	 5.	 	Multiply	the	circuit	compression	factor	(mL/cm	H O)	by	the	peak	inspiratory	pressure	during
                                                                         2
                            mechanical	ventilation	(cm	H O),	or	(peak	inspiratory	pressure–PEEP)	if	PEEP	is	used.
                                                       2
                        Example:

                        Expired	volume	5	150	mL;	Peak	inspiratory	pressure	(Y	occlusion)	5	50	cm	H O;
                                                                                              2
                        Peak	inspiratory	pressure	(mechanical	ventilation)	5	60	cm	H O;	PEEP	5	10	cm	H O.
                                                                                                  2
                                                                                2
                        Circuit	compression	factor	5	150	mL/50	cm	H O	5	3	mL/cm	H O
                                                                                 2
                                                                  2
                        Circuit	compression	volume	5	3	mL/cm	H O	3	(60	2	10)	cm	H O	5	3	3	50	5	150	mL
                                                               2
                                                                                 2
                      © Cengage Learning 2014
                                            #
                                            V     vent :   Inspiratory flow of ventilator, in L/min
                                            #
                                            V      spon :      Inspiratory flow during spontaneous breathing in L/min (obtained via
                                                      flow/time graphic or estimated to be 500 mL/sec or 30 L/min)

                                            As shown in the equation, the level of pressure support needed is partly based on
                                            the PIP and P . For this reason, the PS level must be adjusted on an as-needed
                                                        plat
                                            basis depending on the changing conditions that alter the PIP and P .
                                                                                                      plat
                                             For weaning from mechanical ventilation with a spontaneous breathing trial, PS is
                                            titrated until achieving a spontaneous frequency of 20 to 25/min or a spontaneous
                                            tidal volume of 8 to 10 mL/kg predicted body weight (PBW). A PSV of greater than
                                            30 cm H O is rarely needed since these patients are typically not ready for weaning.
                                                   2
                                            For further weaning, the PS level is reduced by 2 to 4 cm H O increments as toler-
                                                                                              2
                                            ated. Extubation can be considered when the PS level reaches 5 to 8 cm H O for
                                                                                                            2
                                            2 hours with no signs of respiratory distress.

                                            F O  2
                                             I

                          After stabilization of the   For  patients  with  severe  hypoxemia  or  abnormal  cardiopulmonary  functions
                        patient, the F I O 2  is best kept   (e.g., post-resuscitation, smoke inhalation, ARDS), the initial F O  may be set at
                        below 50% to avoid oxygen-                                                 I  2
                        induced lung injuries.  100%. The F O  should be evaluated by means of arterial blood gas analyses after
                                                         2
                                                       I
                                            stabilization of the patient. It should be adjusted accordingly to maintain a PaO
                                                                                                                 2




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