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Initiation of Mechanical Ventilation  231


                                             Types of Hazards and Complications


                                             Prospective  studies  of  patient  outcome  during  mechanical  ventilation  indicate
                                             that hazards and complications are related to (1) positive pressure ventilation (e.g.,
                                             barotrauma, impedance of cardiac output), (2) patient condition (e.g., organ fail-
                                             ure), (3) ventilator and artificial airway (accidental extubation), and (4) medical
                                             professionals (e.g., nosocomial infection). Examples for each of these four areas are
                                             shown in Table 8-13.




                                                TABLE 8-13 Hazards and Complications of Mechanical Ventilation

                                                Condition                      Examples
                                                Related	to	positive	pressure	  Barotrauma	(pneumothorax,
                                                 ventilation                   mediastinal	air	leak,	subcutaneous	air
                                                                                 leak)
                                                                               Hypotension,	decrease	in	cardiac
                                                                                 output
                                                                               Arrhythmia
                                                                               Oxygen	toxicity
                                                                               Bronchopleural	fistula
                                                                               Bronchopulmonary	dysplasia	(in	infants)
                                                                               Upper	gastrointestinal	hemorrhage

                                                Related	to	patient	condition   Infection	(due	to	reduced	immunity)
                                                                               Physical	and	psychologic	trauma
                                                                               Multiple	organ	failure	(may	be
                                                                                 preexisting)
                                                Related	to	equipment	          Ventilator	and	alarm	malfunction
                                                 (ventilator	and	              Ventilator	circuit	disconnection
                                                 artificial	airway)            Accidental	extubation
                                                                               Main	bronchus	intubation
                                                                               Postintubation	stridor
                                                                               Endotracheal	tube	blockage
                                                                               Tissue	damage
                                                                               Atelectasis	(due	to	inadequate	tidal
                                                                                 volume)

                                                Related	to	medical	            Nosocomial	pneumonia	(due	to
                                                 professionals                   cross-contamination)
                                                                               Inappropriate	ventilator	settings
                                                                               Misadventures	(due	to	lapses	of
                                                                                 understanding	and
                                                                                 communication)

                                             (Data	from	Ventilator	alarm	failures,	Bourke	et	al.,	1987;	Milligan,	1992;	Pryn	et	al.,	1989;	Slee	et	al.,	1988;	and	Other
                                             hazards	and	complications:	Bezzant	et	al.,	1994;	Cox	et	al.,	1991;	Liu	et	al.,	1991;	Pierson,	1990;	Rivera	et	al.,	1992.)
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