Page 94 - Clinical Application of Mechanical Ventilation
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60     Chapter 3


                      PHASE VARIABLES



                                            A ventilator-supported breath may be divided into four distinct phases: (1) the change
                                            from expiration to inspiration, (2) inspiration, (3) the change from inspiration to ex-
                                            piration, and (4) expiration. More detail can be learned by studying what occurs to
                                            the four variables (pressure, volume, flow, and time) during these phases. When the
                                            variable is examined during a particular phase, it is termed a phase variable.

                                            Trigger Variable


                                            The trigger variable is the variable that determines the start of inspiration. Pres-
                                            sure, volume, flow, or time may be measured by the ventilator and used as a vari-
                                            able to initiate inspiration. Many ventilators may use time or pressure as trigger
                                            variables.

                                            Control: Time-Triggered. A time-triggered breath is initiated and delivered by the
                      time-triggered: Initiation of a
                      mechanical breath based on the   ventilator when a preset time interval has elapsed. The frequency control on the
                      set time interval for one complete   ventilator is a time-triggering mechanism.
                      respiratory cycle (inspiratory time
                      and expiratory time).  For example, if the  ventilator frequency is preset at 12 breaths per minute (60 sec),
                                            the time-triggering interval for each complete breath is 5 sec. At this time-trigger in-
                                            terval, the ventilator automatically delivers one mechanical breath every 5 sec without
                                            regard to the patient’s breathing effort or requirement.
                                                                 60 sec/12 breaths = 5 sec/breath

                                            Pressure-Triggered. A pressure-triggered breath is initiated and delivered by the
                      pressure-triggered: Initiation of
                      a mechanical breath based on the   ventilator when it senses the patient’s spontaneous (negative pressure) inspiratory
                      drop in airway pressure that occurs   effort. The patient may trigger the ventilator by generating a pressure gradient or a
                      at the beginning of a spontaneous
                      inspiratory effort.   flow gradient.
                                             Pressure triggering uses the drop in airway pressure that occurs at the beginning
                                            of  a  spontaneous  inspiratory  effort  to  signal  the  ventilator  to  begin  inspiration
                                            (Figure 3-9). The amount of negative pressure, below the patient’s baseline airway
                                            pressure (or end-expiratory pressure), that a patient must generate to trigger the
                                            ventilator into inspiration, is the sensitivity level. The range of acceptable sensitiv-
                                            ity levels for pressure triggering varies from 21 to 25 cm H O below the patient’s
                                                                                               2
                                            baseline pressure.
                                             For example, if the sensitivity for pressure triggering is set at 23 cm H O, then
                                                                                                          2
                          Comparing to a sensitiv-  the patient must generate a pressure of 23 cm H O at the airway opening to trigger
                        ity setting of 23 cm H 2 O, 25                              2
                        cm H 2 O requires more patient   the ventilator into inspiration. If the sensitivity for pressure triggering is changed
                        effort to trigger the ventilator   from 23 to 25 cm H O, the ventilator becomes less sensitive to the patient’s in-
                        to inspiration.                        2
                                            spiratory effort as more effort is needed to trigger the ventilator into inspiration.
                                            Changing the sensitivity from 23 to 25 cm H O is decreasing the sensitivity setting
                                                                                   2
                                            on the ventilator.
                                             In situations where auto-PEEP is present, the triggering pressure would become
                                            greater. In order for the ventilator to sense a successful triggering effort, the patient
                                            must overcome both the auto-PEEP level and the sensitivity setting. See Figure 12-2






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