Page 816 - Cardiac Nursing
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                  792    PA R T  V / Health Promotion and Disease Prevention
                   DISPLAY 34-3 Nicotine Replacement Therapy
                    Nicotine Gum                                        also be aware that 8% to 25% of nicotine gum users who
                                                                        successfully quit smoking use the gum beyond the 6
                    Nicotine chewing gum has been available in the United  months recommended for maximal use. Habitual use of
                     States since 1984, and has been available over the  the gum to deal with negative emotional states is often
                     counter since 1997. It comes in 2- and 4-mg doses. It   the cause of this prolonged use. 97  As noted previously,
                     is a resin-based gum that releases nicotine into the   the prolonged use of the gum is preferred to smoking and
                     bloodstream through the buccal mucosa inside the   has not been shown to be harmful. 61
                     mouth. The success of nicotine gum is highly dependent
                     on its proper use. It has been shown to be highly ineffec-  Nicotine Patch
                     tive when dispensed without proper chewing instruction.
                     Moreover, when nicotine gum is prescribed without any  The transdermal nicotine patch has been available in the
                     counseling or strong advice, it has been shown to  United States by prescription since 1991 and over the
                     produce very low cessation rates. 94               counter since 1997. The nicotine patch produces a thera-
                    Patients should start using the gum immediately as soon as  peutic effect by releasing a controlled amount of nicotine
                     they stop smoking. Although nicotine gum was originally  through the skin that is absorbed through the capillary
                     prescribed to be taken on an as-needed basis, studies sug-  bed.
                     gest that a regular schedule of taking the gum, normally  The nicotine patch is designed to be worn for a period
                     one piece every 60 minutes during waking hours, ensures  of 16 to 24 hours depending on the brand, with a
                     constant blood nicotine levels. 95  Side effects are also mini-  recommended dose of 21 mg/24 h, or 15 mg/16 h. Lower
                     mal and transient if the gum is administered properly.  doses (10–14 mg) are recommended for some cardiovas-
                     Most often, these side effects are limited to local mouth ir-  cular patients, see above. Patches are designed to be
                     ritation, some gastrointestinal distress such as nausea and  changed daily and are normally recommended to be used
                     heartburn, palpitations, and jaw ache from excessive  for 8 weeks, with weaning beginning at 4 weeks. During
                     chewing.                                           the weaning period, the dose is reduced in a stepwise
                    An acidic environment in the mouth blocks nicotine absorp-  manner (i.e., 21, 14, and 7 mg) to 7 mg/24 h, or 5 mg/16 h,
                     tion. Because the use of beverages such as colas, coffee,  and finally discontinued. 98  The nicotine patch is often
                     tea, and juices changes the oral pH to an acidic environ-  considered the preferred choice for patients because of
                     ment, these agents should not be used within 15 minutes  ease of use. It requires little effort to apply the patch and
                     of using the gum or during the first 15 minutes of chew-  coverage can be ensured for up to 24 hours.
                     ing the gum. 96  Because nicotine gum is now available  The most frequent side effect of the nicotine patch is local
                     over the counter, it is imperative that teaching be done  skin redness, which occurs in approximately 35% to 54%
                     by the nurse or, alternatively, the patient should be  of patients using the patch. 99–102  Severe skin reactions,
                     encouraged to discuss proper use with a pharmacist.  which include rashes or eczema, have led to discontinua-
                     Nicotine chewing gum is normally used for a period of 3  tion of therapy in less than 7% of patients. 103,104  Other
                     to 6 months. A tapering schedule of at least 1 month is  side effects reported, which occur much less frequently,
                     recommended. Weaning can be accomplished by decreas-  include gastrointestinal problems of dyspepsia, abdomi-
                     ing the dosage, cutting gum pieces in half, and substitut-  nal pain, and diarrhea; muscle and limb weakness; pares-
                     ing sugarless gum for some of the doses. Nurses should  thesia; nervousness; and vivid or disturbing dreams. 105
                  smoking as an addiction. Cigarette smoking has clearly been  trouble-shoot any problems associated with the use of pharma-
                  found to be an addiction because it fulfills the requirements for  cologic therapies.
                  addiction of (1) highly controlled or compulsive use; (2) psy-  Although a brief intervention is the minimum that all health
                  choactive effects; and (3) drug-reinforced behavior. 22  care providers should offer their patients, the guidelines 61,62
                                                                      clearly point out that implementation of a more intensive inter-
                  Step 5: Arrange—Schedule                            vention is the goal because there is a strong dose–response relation
                  Follow-Up Contact                                   between counseling intensity and success in smoking cessation.
                                                                      The meta-analyses conducted for the current guideline strongly
                  The guideline  62  concluded that reinforcement by numerous  indicate that there is a dose–response relationship between session
                  contacts and health care professionals leads to greater smoking  length and abstinence rates, total amount of contact time and ab-
                  cessation rates. Ideally, follow-up contact should occur soon af-  stinence rates, and the number of sessions and treatment efficacy.
                  ter the established quit date, preferably within the first week  In terms of session length, it was found that abstinence rates in-
                  and then again within the first month. Follow-up can be per-  crease from 10.9 with no contact to 22.1 with longer counseling
                  formed in person or by telephone. Important components of  sessions (lasting  10 minutes). In terms of contact time, it was
                  follow-up include congratulations on success, support, rein-  found that abstinence rates increase from 11.0 with no contact
                  forcement, and problem solving. If the patient slipped or re-  time to 28.4 with 91 to 300 minutes. In terms of number of ses-
                  lapsed, follow-up provides the opportunity to review the cir-  sions, abstinence rates double from 12.4 with no or one session to
                  cumstances that led to the slip or relapse, create a new plan to  24.7 with more than eight sessions. The guideline thus recom-
                  deal with a similar situation in the future, and establish a new  mends four or more sessions lasting longer than 10 minutes for a
                  quit date. Follow-up also allows the clinician to review and  total contact time of more than 30 minutes.
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