Page 115 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Abnormalities of Glomerular Permselectivity and Nephrotic Syndrome
Abnormal
Normal Glomerular capillary permselectivity of
1 the glomerular filter
Disorders
Glomerular filter 2
Capsular
space

1.0 Normal 1.0 Glomerulonephritis
Fractional excretion 0.6 – n + Fractional excretion 0.6 – + Glomerular Permselectivity:
0.8
0.8
0.4
0.4
0.2
0 0.2 0
180 240 300 360 420 180 240 300 360 420
Molecular size (nm) Molecular size (nm)
3 Urine Plate 5.7
electrophoresis Tubular reabsorption

Proteinuria
Albumin Lipoprotein lipase
deficiency
4 Serum Lipoprotein ?
electrophoresis Hypoproteinemia synthesis
Normal 6
Albumin Immuno- globulins Hyperlipidemia
Oncotic pressure in
the vascular system
decreases
5 Damage to
peripheral capillaries
P Filtration
Pressure Edema 7

π
Resorption
Hypovolemia
Lenght of capillary
ADH
Hypokalemia Aldosterone

Alkalosis 105

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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