Page 139 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Deranged Calcium Metabolism
Alkali Inactivity Tumor cells

Ca 2+ Interleukin
2
Calcitriol Ca 2+ Ca 2+ Renal
retention
PTH
D 3 excess 25-OH-D 3 Abnormalities of Calcium Balance

Hypercalcemia
5
g +
K
Heart:
– Shortening of
action potentials
– Increased Precipitation
digitalis sensitivity Plate 5.19
Nephrocalcinosis,
keratitis
Psychiatric ? 4
disorders Tight junctions
less permeable
Polyuria, Heart:
magnesiuria, – Prolonging of
constipation, action potentials
indigestion, g +
K
nausea Tetany,
paresthesias
g Na +
Hypocalcemia
D 3 deficiency
25-OH-D 3
PTH 2+
2+
Ca bound Ca
Ca 2+ 1
Calcitriol HPO 4 2–
2– FS –
HPO 4
Prot –
H +
Ca 2+
Alkalosis
Ca 2+ 3
Prot –
Decreased Lack of Formation of
intestinal mobilization complexes
absorption 2+
Renal Ca loss,
2–
renal HPO 4 retention 129
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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