Page 19 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

Ca 2+
Receptor defects
II
3
R o
β
γ Signal Transmission I +
α o
Activated
GTP G o protein
Ca 2+ channel
6 Phospho- Phospholipase inhibitor
lipase C + 1.4
PIP 2
Phospho-
Lithium lipase A 9 Plate 1.3
Inositol IP 3
DAG
7 IP 1 Arachidonic
Lip- acid
oxygenase
LO inhibitor Cyclo-
Phorbol ester oxygenase
Ca 2+
8
Leukotriene CO inhibitor
Protein kinase C
Ca 2+
stored in Prostaglandins
organelles
5
Calmodulin cGMP Guanylyl cyclase

GTP
Protein TNF
CaM kinase G
kinase
11
Ceramide Sphingomyelinase

Sphingomyelin
Enzymes
Transport proteins
Transcription factors Cell interior Cell membrane 9

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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