Page 211 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Causes and Consequences of Aortic Regurgitation
Rheumatic Bakterial Marfan’s
Congenital fever endocarditis syndrome Syphilis Arthritis etc.
Systole Diastole
Aortic valve

Thickened,
stiffed, Regurgitant volume
perforated Regurgitation
Aortic regurgitation
Diastolic Effective
blood pressure stroke volume
1s Aortic
ECG Compensation
Ventricular dilation End-diastolic
mmHg volume
150 Laplace’s
law Plate 7.14
Wall tension Total
100 P Ao stroke volume
LV hypertrophy
50 P LV Effective
stroke volume
P LA normalized
O 2 consumption
0
SM EDM Years to
Basis decades
Myocardial hypoxia
MDM
Apex (angina pectoris) Decompensation
Heart
sounds II I Click Left heart failure
1 (after Criley)
Effective
stroke volume
Normal Compensated Decompensated
Ventricular
EDV dilation
mmHg ESV SV
100 Diastole (after Rackley et al.) Functional Ventricular
Left ventricular pressure = P LV 50 Systole regurgitation compliance
mitral

0
0 0.1 0.2 0.3 0.4 0.5 Left atrial pressure
LV volume (L)
2
Pulmonary Left heart
edema failure 201
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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