Page 207 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Causes and Consequences of Mitral Regurgitation
                         Valvar prolapse  Coronary  Marfan’s
               Endocarditis
                          (Barlow)  heart disease  syndrome
                                                   Left atrium:
           Left ventricle:                         distended
           ischemia, fibrosis,
           aneurysm                                Valve ring:
                                                   deformed, stiffened
           Chordae:
           too long, too short,                    Leaflets:
           rupture                                 shrunk, thickened,
                                                   stiffened, prolapsing
           Papillary muscle:
           fibrosis, rupture                                           Mitral Regurgitation
                         Regurgitant
                          volume                    ECG   P ‘mitrale’
                                                 mm
                                                 Hg
                                                       P Ao
                                                 100
             Diastole         Systole                     v  P LV      Plate 7.12
                                                 50   a  P LA
                               Mitral regurgitation
            ECG                                         SM    RFW
                                                  0
        100         P Ao   Chronic          Acute
        mm                                        Heart sounds  I  II III IV
        Hg                                         0  2  4  6  8  10
         50  P LA  v         high  Atrial compliance  low  Time (s)  (after Criley)
                       P LV
           a     y
          0  x SM  RFW
         Heart sounds  I  II III  I  Volume  Atrial pressure  ‘Forward’ CO
                                          (P LA )
                             load
                       8
               2
             0
                         10
              Time (s) 4  6 (after Criley)
                                         Dsypnea,       Systolic
                                         hemoptysis     pressure
                             Mitral
                         regurgitation
             Atrial dilation
                                       Pulmonary edema  Tachycardia
             Atrial damage
                               Ventricular  Pulmonary   Regurgitant
                                                         volume
            Tachyarrhythmia    dilation  hypertension
              Regurgitant                           Mitral regurgitation
               volume       Left heart   Right heart
                             failure       failure                    197
       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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