Page 219 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
P. 219

A.  Principles of the Development of Hypertension

                        Arterial blood pressure =
                  Cardiac output       x        Total peripheral resistance
                         (CO)                                       (TPR)
          Extracellular volume                Angiotensin II

                                                         CNS
                           CNS
                                           Vascular
                                         hyperreactivity
           Central                                      Adrenal
           blood volume                                 medulla        Hypertension I

                        Catecholamines
                 Venous                        Vasoconstriction
                  tone       T 3 , T 4 ,
                             cortisol                                  Plate 7.18

                    CO                             TPR



                              Vascular resistance (radius)
                                        pressure
                          Organ perfusion  constant  Autoregulation
                                        dependent


             Hyperdynamic
             hypertension
                          0
                           0    Systemic blood pressure  Resistance
                                                     hypertension


                                                Vicious
                                                circle




                    Photo: U.Pfeifer      Hypertrophy of              209
                                          vessel musculature and
                                          vascular damage:
                                          fixation of hypertension

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
   214   215   216   217   218   219   220   221   222   223   224