Page 27 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Tumors: Failure of Lymphocytic Defense, Local Damage, and Metastases
Lymphocyte
Tumor
cell Migration
CD95 Penetration
ligand
Blood stream
Neuronal
displacement Adhesion
Apoptosis Intracranial Penetration
pressure
Proliferation
Epilepsy
1 of Tumors
Lymphocytic 2
defense Local damage, 3
e.g. brain tumor
Metastatic spread Effects
B. Effects of Tumors
Tumors
Plate 1.8
Death of tumor cells Energy
requirement

K +
Uric Glucose Hypoglycemia
acid consumption
Hyper- Abnormal
kalemia blood clotting Glucagon
Insulin,
somato- Cortisol
Hyper- medines
uricemia Blood Iron
loss consumption Catecholamines
Lactate+H +
Antibodies
Iron deficiency Angiogenesis Blood
pressure
Acidosis
Cardiac
Anemia output Hormonal Aldosterone
disorders
Tumor
cachexia
Myasthenia
Parathyroid
hormone, Testosterone VIP, TSH ADH
DAF serotonin
Prolactin Gastrin Somato-
CaHPO 4 tropin
Hyper- Hyper-
Renal Virilization Diarrhea thyroidism hydration
damage
Bone
breakdown Galactorrhea Ulcers Acromegaly 17
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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