Page 295 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Effects and Symptoms of Hypothyroidism
                         Filtration of albumin  Impaired cerebral
         Depostion of     Na  retention   development
                           +
         glycosamineglycans
         (mucin)                                                       Symptoms
                            Edema
                                              7
                            Effusion,          Neuromuscular           and
                            hoarse voice,      excitability
                4           puffed-up face                             Effects
                  Myxedema                        Sensory disturbances
                                                    Hyporeflexia
                                                    Lack of drive
            Vitamin A                               Depression
                Sebaceous                           Clouded consciousness  Hypothyroidism:
                and sweat
                gland activity
             Dry, scaly skin
                                                                       Plate 9.15
        1     Energy
            metabolism
                                                        Renal
              Heat                                      blood flow
            metabolism                                  Glomerular
                                                        filtration
           Sensitivity to cold
           Appetite                                     Transport
           Erythropoiesis                             Salt and
                                                      water retention
                                   Hypothyroidism    6
         Delayed breakdown
         of VLDL
         Reduced        Reduced lipolysis            Intestinal
         bile secretion  2                            motility
                                                      Obstipation
             VLDL          Overweight                 Reflux esophagitis
             Cholesterol
                                                       8
                                                      In children:
            Atherosclerosis                           retarded
                                                      longitudinal growth
                                                      and delayed
               5                                      epiphyseal fusion
                                       Protein synthesis
         Cardiac                       Elimination of  somatotropin
                                                      release
         contractility             3   drugs
         Bradycardia                   Glycogenolysis    Small stature
                                       Gluconeogenesis   Cretinism
                   CO
                                         Hypoglycemia                 285

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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