Page 299 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Acute Effects of Diabetes Mellitus
                              Acute insulin deficiency
               Proteolysis                        Lipolysis

                                      Weight
                                       loss                            Effects
                  Muscle weakness
                                                     Fatty acids in blood
                                    Fatty liver
            Amino acids                                                Mellitus: Acute
                                Glycogen           VLDL
                                breakdown
                           Gluco-
                           neogenesis                      LDL         Diabetes
                                       1

                          Glucose excess                               Plate 9.17
                           Mg 2+               Osmolarity

                                                     Ketone bodies
                             P i
                                             Reduced
                    H 2 O           H +      glycolysis
                H +
                                     Na +                    H +
                            Na +
                                     K +
                                                            Acidosis
                            K +      Na +
                                     2Cl –



                  Kidney                           Coma        3

                             Aldosterone

                                                     Fruit-lozenge
                             Dehydration               breath
              2
          Glucosuria           Thirst               Kussmaul breathing
          Aminoaciduria
          Polyuria
          Electrolyte loss
                                                                      289


       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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