Page 315 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Disorders of Neuromuscular Transmission
Action potential
Disorders
Local
anesthetics
Na + Botulinus toxin
Neuromuscular Transmission:
Ca 2+
2+
Mg , hemicholine
Antibodies ACh Physostigmine
Suxamethonium Curare

Na + ACh-esterase
Muscle cell Plate 10.4
Contraction

B. Myasthenia Gravis C. Pseudomyasthenic Syndrome
Viral infection
Genetic
disposition
DR3, Lung carcinoma
DQw2 Ca 2+
Thymoma

Sensitization
2+
against Ca channels
Sensitization of the tumor cells
against ACh receptor- Antibody
like structure formation
Antibody
formation
1
Repetitive stimulation
Repetitive stimulation 1
1mV 1mV
2
2 50ms 50ms
Lambert-Eaton
Myasthenia gravis myasthenic syndrome 305

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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