Page 57 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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B lymphocytes
                                                    B cell
                                                  IgD-, IgM-
                                                  monomer
                              Antigen binding  Antibody
                                               enmeshing               II + III
                                                         Activation
              ‘Naive’ B cell                                           Defense
                                                                       Immune
                                  3                      Internalization


                                                                       + 3.10

                                                                       Plate 3.9
                                                         Preparation

                Cooperation of
               T H2  cell and B cell
     T H2  cell                    B cell
                              TD  HLA II
             CD4             antigen
        T-cell receptor                                    HLA II
        CD40 ligand       CD40          Presentation
     4
                   IL-4
                  IL-5
                  IL-6
                                  Proliferation


                                                    Plasma cell
                    5            Differentiation


                                                     According to class jump
                                                      Immune
                              IgM         IgG  IgA  IgE  globulins
                               Specific humoral immune defense
                                       (see A)                        47

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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