Page 97 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Causes of Alkalosis
1 Consumption of organic anions 2 Demineralization 3 Hyperventilation
Lactate, Metabolism
dissociated
fatty acids,
etc. 2–
CO 3
3–
PO 4
+
+
H consumption H
CO 2 output Alkalosis
–
H 2 PO 4 with expiration
–
HCO 3
K + HCl 6
– – Vomiting Development of
+ HCO 3
Hypo- Hypo- K +
kalemia volemia + –
4 H HCO 3
K + Plate 4.11
+ – CO 2
– +
3HCO 3 Na
Proximal H +
Na + tubules 7
Hypopara- Liver failure
thyroidism
5 Aldosterone
Urea
H +
–
HCO 3
Distal nephron +
NH 4
–
+
H excretion HCO 3 consumption
–
HCO 3 production
Cys Lys Arg
Met +
–
H + [H ] [HCO 3 ] [CO 2 ]
2– PrH
SO 4 Pr
Protein deficiency
8 H 2 O
–
[HCO 3 ]
pH = pK + lg >7.45 Alkalosis
[CO 2 ] 87
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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