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Neurological Alterations


                                                       and Management                                     17





                                                                             Di Chamberlain
                                                                                Wendy Corkill



                                                                  of diseases such as stroke, brain and spinal cord injury,
               Learning objectives                                and status epilepticus. This chapter discusses the concepts
                                                                  that  underlie  neurological  abnormalities  and  addresses
               After reading this chapter, you should be able to:  current management techniques and modalities.
               ●   differentiate cerebral hypoxia from cerebral ischaemia and
                   focal from global ischaemia                    CONCEPTS OF NEUROLOGICAL
               ●   differentiate between primary and secondary brain injuries   DYSFUNCTION
                   due to brain injury
               ●   relate the procedures of selected neurodiagnostic tests to   This  section  discusses  the  concepts  of  neurological
                                                                  dysfunction  including  altered  levels  of  consciousness,
                   nursing implications for patient care          motor  and  sensory  function  and  cerebral  metabolism
               ●   discuss the rationale for medical and nursing management   and perfusion.
                   in the care of the brain-injured patient.
                                                                  ALTERATIONS IN CONSCIOUSNESS
                                                                  In critical illness, impaired consciousness is often the first
                                                                  sign  of  a  severe  pathological  process.  Consciousness  is
               Key words                                          defined as recognition of self and the environment, which
                                                                  requires both arousal and awareness. There are different
               coma                                               types of depressed consciousness through to coma, the
               cerebral perfusion                                 most severe form of absolute unconsciousness.
               neuroprotection
               intracranial hypertension                          Altered Cognition and Coma
               seizures                                           Coma  is  a  state  of  unresponsiveness  from  which  the
               traumatic brain injury                             patient, who appears to be asleep, cannot be aroused by
               stroke                                             verbal and physical stimuli to produce any meaningful
               spinal cord injury                                 response;  therefore,  the  diagnosis  of  coma  implies  the
                                                                  absence of both arousal and content of consciousness.
                                                                                                                  1
               meningitis                                         Coma  must  be  considered  a  symptom  with  numerous
               subarachnoid haemorrhage
                                                                  causes, different natural modes, and several management
                                                                  modes.
                                                                  Stupor  is  a  state  of  unconsciousness  from  which  the
             INTRODUCTION                                         patient can be awakened to produce inadequate responses
                                                                  to verbal and physical stimuli.
             There  are  numerous  conditions  encountered  in  critical
             care areas that relate to serious neurological dysfunction.   Somnolence is a state of unconsciousness from which the
             While most are associated with critical illness, or at least   patient can be fully awakened. Although there are many
             well  defined,  several  others  are  very  infrequent  and    specific causes of unconsciousness, the sites of cerebral
             not addressed extensively in this chapter. One problem   affection  are  either  the  bilateral  cerebral  cortex  or  the
             arises in that the onset of an abrupt neurological com-  brainstem  reticular  activating  system.  The  commonest
             plication  is  frequently  obscured  by  the  effects  of  the   causes  of  bilateral  cortical  disease  are  deficiencies  of
             primary  illness.  For  example  a  metabolic  disorder  pro-  oxygen, metabolic disorders, physical injury, toxins, post-
                                                                                              2
             ducing encephalopathy can delay recognition of an intra-  convulsive coma and infections.  The reticular activating
             cerebral haemorrhage, or by its treatment, such as using   system  maintains  the  state  of  wakefulness  through
             sedation  to  allow  greater  synchrony  with  a  mechanical   continuous  stimulation  of  the  cortex.  Any  interruption
             ventilator. However, neurological alterations are generally   may  lead  to  unconsciousness.  The  reticular  activating
             defined by problems that derive from the acute aspects    system  can  be  affected  in  three  principal  ways:  by   445
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