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1574   Part IX  Cell-Based Therapies


           T lymphocytes targeting Epstein-Barr virus latent membrane proteins.    22.  Morgan  RA,  Chinnasamy  N,  bate-Daga  D,  et al:  Cancer  regression
           J Clin Oncol 32:798–808, 2014.                        and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
        13.  Robbins  PF,  Lu  YC,  El-Gamil  M,  et al:  Mining  exomic  sequencing   J Immunother 36:133–151, 2013.
           data to identify mutated antigens recognized by adoptively transferred   23.  Ramos CA, Savoldo B, Dotti G: CD19-CAR trials. Cancer J 20:112–118,
           tumor-reactive T cells. Nat Med 19:747–752, 2013.     2014.
        14.  Rizvi NA, Hellmann MD, Snyder A, et al: Mutational landscape deter-  24.  Lee DW, Kochenderfer JN, Stetler-Stevenson M, et al: T cells expressing
           mines sensitivity to PD-1 blockade in non-small cell lung cancer. Science   CD19  chimeric  antigen  receptors  for  acute  lymphoblastic  leukaemia
           2015.                                                 in  children  and  young  adults:  a  phase  1  dose-escalation  trial.  Lancet
        15.  Morgan  RA,  Dudley  ME, Wunderlich  JR,  et al:  Cancer  regression  in   385:517–528, 2015.
           patients  after  transfer  of  genetically  engineered  lymphocytes.  Science   25.  Kochenderfer  JN,  Dudley  ME,  Kassim  SH,  et al:  Chemotherapy-
           314:126–129, 2006.                                    Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malig-
        16.  Dotti  G,  Gottschalk  S,  Savoldo  B,  et al:  Design  and  development  of   nancies Can Be Effectively Treated With Autologous T Cells Expressing
           therapies  using  chimeric  antigen  receptor-expressing T  cells.  Immunol   an Anti-CD19 Chimeric Antigen Receptor. J Clin Oncol 33:540–549,
           Rev 257:107–126, 2014.                                2015.
        17.  Robbins  PF,  Morgan  RA,  Feldman  SA,  et al:  Tumor  regression  in   26.  Wang QS, Wang Y, Lv HY, et al: Treatment of CD33-directed chimeric
           patients  with  metastatic  synovial  cell  sarcoma  and  melanoma  using   antigen receptor-modified T cells in one patient with relapsed and refrac-
           genetically  engineered  lymphocytes  reactive  with  NY-ESO-1.  J  Clin   tory acute myeloid leukemia. Mol Ther 23:184–191, 2015.
           Oncol 29:917–924, 2011.                            27.  Gattinoni L, Lugli E, Ji Y, et al: A human memory T cell subset with
        18.  Arber C, Feng X, Abhyankar H, et al: Survivin-specific T cell receptor   stem cell-like properties. Nat Med 17:1290–1297, 2011.
           targets tumor but not T cells. J Clin Invest 125:157–168, 2015.  28.  Xu Y, Zhang M, Ramos CA, et al: Closely related T-memory stem cells
        19.  Parkhurst MR, Yang JC, Langan RC, et al: T cells targeting carcinoem-  correlate with in vivo expansion of CAR.CD19-T cells and are preserved
           bryonic antigen can mediate regression of metastatic colorectal cancer   by IL-7 and IL-15. Blood 123:3750–3759, 2014.
           but induce severe transient colitis. Mol Ther 19:620–626, 2011.  29.  Conlon KC, Lugli E, Welles HC, et al: Redistribution, hyperprolifera-
        20.  Bendle  GM,  Linnemann  C,  Hooijkaas  AI,  et al:  Lethal  graft-versus-  tion,  activation  of  natural  killer  cells  and  CD8 T  cells,  and  cytokine
           host disease in mouse models of T cell receptor gene therapy. Nat Med   production during first-in-human clinical trial of recombinant human
           16:565–570, 1p, 2010.                                 interleukin-15 in patients with cancer. J Clin Oncol 33:74–82, 2015.
        21.  Linette  GP,  Stadtmauer  EA,  Maus  MV,  et al:  Cardiovascular  toxicity   30.  Topalian SL, Hodi FS, Brahmer JR, et al: Safety, activity, and immune
           and  titin  cross-reactivity  of  affinity-enhanced T  cells  in  myeloma  and   correlates of anti-PD-1 antibody in cancer. N Engl J Med 366:2443–2454,
           melanoma. Blood 122:863–871, 2013.                    2012.
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