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Chapter 107  Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies  1649.e3


             82.  MacMillan ML, Weisdorf DJ, Brunstein CG, et al: Acute graft-versus-  99.  Ponce  DM,  Gonzales  AM,  Lubin  M,  et al:  Successful Treatment  of
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                with  lymphoid  malignancies:  a  study  by  the  Eurocord-Netcord  and   plantation  for  older  patients  with  acute  myeloid  leukemia  in  first
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             84.  Lindemans CA, Chiesa R, Amrolia PJ, et al: Impact of thymoglobulin   20(6):816–822, 2014.
                prior  to  pediatric  unrelated  umbilical  cord  blood  transplantation  on   101.  Rodrigues CA, Rocha V, Dreger P, et al: Alternative donor hematopoi-
                immune reconstitution and clinical outcome. Blood 123(1):126–132,   etic stem cell transplantation for mature lymphoid malignancies after
                2014.                                                 reduced-intensity conditioning regimen: similar outcomes with umbili-
             85.  Cutler C, Stevenson K, Kim HT, et al: Double umbilical cord blood   cal cord blood and unrelated donor peripheral blood. Haematologica
                transplantation  with  reduced  intensity  conditioning  and  sirolimus-  99(2):370–377, 2014.
                based  GVHD  prophylaxis.  Bone  Marrow Transplant  46(5):659–667,   102.  Marks DI, Woo KA, Zhong X, et al: Unrelated umbilical cord blood
                2011.                                                 transplant for adult acute lymphoblastic leukemia in first and second
             86.  Jacobson CA, Turki AT, McDonough SM, et al: Immune reconstitution   complete remission: a comparison with allografts from adult unrelated
                after double umbilical cord blood stem cell transplantation: comparison   donors. Haematologica 99(2):322–328, 2014.
                with unrelated peripheral blood stem cell transplantation. Biol Blood   103.  Kai S, Wake A, Okada M, et al: Double-unit cord blood transplanta-
                Marrow Transplant 18(4):565–574, 2012.                tion  after  myeloablative  conditioning  for  patients  with  hematologic
             87.  Brunstein CG, Weisdorf DJ, DeFor T, et al: Marked increased risk of   malignancies: a multicenter phase II study in Japan. Biol Blood Marrow
                Epstein-Barr virus-related complications with the addition of antithy-  Transplant 19(5):812–819, 2013.
                mocyte globulin to a nonmyeloablative conditioning prior to unrelated   104.  Arcese W: Myeloablative versus Reduced Intensity Conditioning Regimen
                umbilical cord blood transplantation. Blood 108(8):2874–2880, 2006.  Cord Blood Transplants. Paper presented at: 37th Annual Meeting of the
             88.  Majhail  NS,  Brunstein  CG,  Tomblyn  M,  et al:  Reduced-intensity   EGBMT; April 4, 2011, 2011; Paris.
                allogeneic transplant in patients older than 55 years: unrelated umbilical   105.  Tucunduva L, Ruggeri A, Sanz G, et al: Impact of Myeloablative and
                cord blood is safe and effective for patients without a matched related   Reduced Intensity Conditioning on Outcomes After Unrelated Cord
                donor. Biol Blood Marrow Transplant 14(3):282–289, 2008.  Blood Transplantation for Adults with Acute Lymphoblastic Leukemia.
             89.  Brunstein  CG,  Fuchs  EJ,  Carter  SL,  et al:  Alternative  donor  trans-  Biol Blood Marrow Transplant 19(2):S127, 2013.
                plantation  after  reduced  intensity  conditioning:  results  of  parallel   106.  Gutman JA, Leisenring W, Appelbaum FR, et al: Low relapse without
                phase 2 trials using partially HLA-mismatched related bone marrow or   excessive transplant-related mortality following myeloablative cord blood
                unrelated double umbilical cord blood grafts. Blood 118(2):282–288,   transplantation for acute leukemia in complete remission: a matched
                2011.                                                 cohort analysis. Biol Blood Marrow Transplant 18(9):1122–1129, 2009.
             90.  Brunstein CG, Eapen M, Ahn KW, et al: Reduced-intensity condition-  107.  Brunstein CG, Gutman JA, Weisdorf DJ, et al: Allogeneic hematopoi-
                ing transplantation in acute leukemia: the effect of source of unrelated   etic cell transplantation for hematologic malignancy: relative risks and
                donor stem cells on outcomes. Blood 119(23):5591–5598, 2012.  benefits  of  double  umbilical  cord  blood.  Blood  116(22):4693–4699,
             91.  Chen  YB,  Aldridge  J,  Kim  HT,  et al:  Reduced-intensity  condition-  2010.
                ing  stem  cell  transplantation:  comparison  of  double  umbilical  cord   108.  Konuma T, Kato S, Ooi J, et al: Comparable long-term outcome of
                blood  and  unrelated  donor  grafts.  Biol  Blood  Marrow  Transplant   unrelated  cord  blood  transplantation  with  related  bone  marrow  or
                18(5):805–812, 2012.                                  peripheral blood stem cell transplantation in patients aged 45 years or
             92.  Robin  M,  Ruggeri  A,  Labopin  M,  et al:  Comparison  of  unrelated   older with hematologic malignancies after myeloablative conditioning.
                cord  blood  and  peripheral  blood  stem  cell  transplantation  in  adults   Biol Blood Marrow Transplant 20(8):1150–1155, 2014.
                with  myelodysplastic  syndrome  after  reduced-intensity  conditioning   109.  Liu HL, Sun ZM, Geng LQ, et al: Similar survival, but better quality
                regimen: a collaborative study from Eurocord (Cord blood Committee   of life after myeloablative transplantation using unrelated cord blood vs
                of Cellular Therapy & Immunobiology Working Party of EBMT) and   matched sibling donors in adults with hematologic malignancies. Bone
                Chronic  Malignancies  Working  Party.  Biol  Blood  Marrow Transplant   Marrow Transplant 49(8):1063–1069, 2014.
                21(3):489–495, 2015.                              110.  Fanning  LR,  Hegerfeldt  Y,  Tary-Lehmann  M,  et al:  Allogeneic
             93.  Rodrigues CA, Rocha V, Dreger P, et al: Alternative donor hematopoi-  transplantation of multiple umbilical cord blood units in adults: role
                etic stem cell transplantation for mature lymphoid malignancies after   of  pretransplant-mixed  lymphocyte  reaction  to  predict  host-vs-graft
                reduced-intensity conditioning regimen: similar outcomes with umbili-  rejection. Leukemia 22(9):1786–1790, 2008.
                cal cord blood and unrelated donor peripheral blood. Haematologica   111.  Brunstein  CG,  Barker  JN,  Weisdorf  DJ,  et al:  Intra-BM  injection
                99(2):370–377, 2014.                                  to  enhance  engraftment  after  myeloablative  umbilical  cord  blood
             94.  Warlick ED, Peffault de Latour R, Shanley R, et al: Allogeneic hema-  transplantation with two partially HLA-matched units. Bone Marrow
                topoietic  cell  transplantation  outcomes  in  acute  myeloid  leukemia:   Transplant 43(12):935–940, 2009.
                similar outcomes regardless of donor type. Biol Blood Marrow Transplant   112.  Frassoni F, Gualandi F, Podesta M, et al: Direct intrabone transplant of
                21(2):357–363, 2015.                                  unrelated cord-blood cells in acute leukaemia: a phase I/II study. Lancet
             95.  Cutler  C,  Ballen  K:  Reduced-intensity  conditioning  and  umbili-  Oncol 9(9):831–839, 2008.
                cal  cord  blood  transplantation  in  adults.  Bone  Marrow  Transplant   113.  Bautista G, Cabrera JR, Regidor C, et al: Cord blood transplants sup-
                44(10):667–671, 2009.                                 ported  by  co-infusion  of  mobilized  hematopoietic  stem  cells  from  a
             96.  Thomson BG, Robertson KA, Gowan D, et al: Analysis of engraftment,   third-party donor. Bone Marrow Transplant 43(5):365–373, 2009.
                graft-versus-host  disease,  and  immune  recovery  following  unrelated   114.  Liu  H,  Rich  ES,  Godley  L,  et al:  Reduced-intensity  conditioning
                donor cord blood transplantation. Blood 96(8):2703–2711, 2000.  with combined haploidentical and cord blood transplantation results
             97.  Soiffer RJ, Lerademacher J, Ho V, et al: Impact of immune modula-  in  rapid  engraftment,  low  GVHD,  and  durable  remissions.  Blood
                tion with anti-T-cell antibodies on the outcome of reduced-intensity   118(24):6438–6445, 2011.
                allogeneic  hematopoietic  stem  cell  transplantation  for  hematologic   115.  de  Lima  M,  McMannis  J,  Gee  A,  et al:  Transplantation  of  ex  vivo
                malignancies. Blood 117(25):6963–6970, 2011.          expanded  cord  blood  cells  using  the  copper  chelator  tetraethyl-
             98.  Sauter C, Abboud M, Jia X, et al: Serious infection risk and immune   enepentamine:  a  phase  I/II  clinical  trial.  Bone  Marrow  Transplant
                recovery after double-unit cord blood transplantation without antithy-  41(9):771–778, 2008.
                mocyte  globulin.  Biol  Blood  Marrow  Transplant  17(10):1460–1471,   116.  Stiff PJ, Montesinos P, Peled T, et al: StemEx®(Copper Chelation Based)
                2011.                                                 Ex Vivo Expanded Umbilical Cord Blood Stem Cell Transplantation
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