Page 2122 - Hematology_ Basic Principles and Practice ( PDFDrive )

Chapter 125 Molecular Basis of Platelet Function 1884.e1

REFERENCES 25. Sidhu TS, French SL, Hamilton JR: Differential signaling by protease-
activated receptors: implications for therapeutic targeting. Int J Mol Sci
1. Franco AT, Corken A, Ware J: Platelets at the interface of thrombosis, 15(4):6169–6183, 2014.
inflammation, and cancer. Blood 126(5):582–588, 2015. 26. Cattaneo M: P2Y12 receptors: structure and function. J Thromb Haemost
2. McFadyen JD, Kaplan ZS: Platelets are not just for clots. Transfus Med 13(Suppl 1):S10–S16, 2015.
Rev 29(2):110–119, 2015. 27. Capra V, Back M, Angiolillo DJ, et al: Impact of vascular throm-
3. Stegner D, Dutting S, Nieswandt B: Mechanistic explanation for platelet boxane prostanoid receptor activation on hemostasis, thrombosis,
contribution to cancer metastasis. Thromb Res 133(Suppl 2):S149–S157, oxidative stress, and inflammation. J Thromb Haemost 12(2):126–137,
2014. 2014.
4. Atkinson B, Dwyer K, Enjyoji K, et al: Ecto-nucleotidases of the CD39/ 28. Brass LF, Newman DK, Wannermacher KM, et al: Signal transduction
NTPDase family modulate platelet activation and thrombus formation: during platelet plug formation. In Michelson AD, editor: Platelets, ed 3,
Potential as therapeutic targets. Blood Cells Mol Dis 36(2):217–222, San Diego, 2013, Academic Press, pp 367–398.
2006. 29. Ozaki Y, Suzuki-Inoue K, Inoue O: Platelet receptors activated via
5. Herr AB, Farndale RW: Structural insights into the interactions between mulitmerization: glycoprotein VI, GPIb-IX-V, and CLEC-2. J Thromb
platelet receptors and fibrillar collagen. J Biol Chem 284(30):19781– Haemost 11(Suppl 1):330–339, 2013.
19785, 2009. 30. Senis YA, Mazharian A, Mori J: Src family kinases: at the forefront of
6. Mendolicchio GL, Ruggeri ZM: New perspectives on von Willebrand platelet activation. Blood 124(13):2013–2024, 2014.
factor functions in hemostasis and thrombosis. Semin Hematol 42(1):5– 31. Harper MT, Poole AW: Diverse functions of protein kinase C isoforms
14, 2005. in platelet activation and thrombus formation. J Thromb Haemost
7. Cho J, Mosher DF: Role of fibronectin assembly in platelet thrombus 8(3):454–462, 2010.
formation. J Thromb Haemost 4(7):1461–1469, 2006. 32. Laurent PA, Severin S, Gratacap MP, et al: Class I PI 3-kinases signaling
8. Inoue O, Suzuki-Inoue K, Ozaki Y: Redundant mechanism of platelet in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact
adhesion to laminin and collagen under flow: involvement of von Wil- of PTEN and SHIP1. Adv Biol Regul 54:162–174, 2014.
lebrand factor and glycoprotein Ib-IX-V. J Biol Chem 283(24):16279– 33. Woulfe DS: Akt signaling in platelets and thrombosis. Expert Rev
16282, 2008. Hematol 3(1):81–91, 2010.
9. Jurk K, Clemetson KJ, de Groot PG, et al: Thrombospondin-1 34. Varga-Szabo D, Braun A, Nieswandt B: STIM and Orai in platelet
mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): function. Cell Calcium 50(3):270–278, 2011.
an alternative/backup mechanism to von Willebrand factor. FASEB J 35. Aslan JE, McCarty OJ: Rho GTPases in platelet function. J Thromb
17(11):1490–1492, 2003. Haemost 11(1):35–46, 2013.
10. Savage B, Saldivar E, Ruggeri ZM: Initiation of platelet adhesion by 36. Italiano JE, Jr, Bergmeier W, Tiwari S, et al: Mechanisms and implica-
arrest onto fibrinogen or translocation on von Willebrand factor. Cell tions of platelet discoid shape. Blood 101(12):4789–4796, 2003.
84(2):289–297, 1996. 37. Freson K, De Vos R, Wittevrongel C, et al: The TUBB1 Q43P func-
11. Reheman A, Gross P, Yang H, et al: Vitronectin stabilizes thrombi and tional polymorphism reduces the risk of cardiovascular disease in men
vessel occlusion but plays a dual role in platelet aggregation. J Thromb by modulating platelet function and structure. Blood 106(7):2356–2362,
Haemost 3(5):875–883, 2005. 2005.
12. Ruggeri ZM: Platelet adhesion under flow. Microcirculation 16(1):58–83, 38. Cerecedo D: Platelet cytoskeleton and its hemostatic role. Blood Coagul
2009. Fibrinolysis 24(8):798–808, 2013.
13. Shoulders MD, Raines RT: Collagen structure and stability. Annu Rev 39. Kunishima S, Saito H: Advances in the understanding of MYH9 disor-
Biochem 78:929–958, 2009. ders. Curr Opin Hematol 17(5):405–410, 2010.
14. Savage B, Almus-Jacobs F, Ruggeri ZM: Specific synergy of multiple 40. Marks MS, Heijnen HF, Raposo G: Lysosome-related organelles: unusual
substrate-receptor interactions in platelet thrombus formation under compartments become mainstream. Curr Opin Cell Biol 25(4):495–505,
flow. Cell 94(5):657–666, 1998. 2013.
15. Bryckaert M, Rosa JP, Denis CV, et al: Of von Willebrand factor and 41. Huizing M, Helip-Wooley A, Westbroek W, et al: Disorders of lysosome-
platelets. Cell Mol Life Sci 72(2):307–326, 2015. related organelle biogenesis: clinical and molecular genetics. Annu Rev
16. Ni H, Yuen PS, Papalia JM, et al: Plasma fibronectin promotes throm- Genomics Hum Genet 9:359–386, 2008.
bus growth and stability in injured arterioles. Proc Natl Acad Sci USA 42. Albers CA, Cvejic A, Favier R, et al: Exome sequencing identifies
100(5):2415–2419, 2003. NBEAL2 as the causative gene for gray platelet syndrome. Nat Genet
17. Li R, Emsley J: The organizing principle of the platelet glycoprotein 43(8):735–737, 2011.
Ib-IX-V complex. J Thromb Haemost 11(4):605–614, 2013. 43. Gunay-Aygun M, Falik-Zaccai TC, Vilboux T, et al: NBEAL2 is mutated
18. Andrews RK, Berndt MC: The GPIb-IX-V complex. In Michelson in gray platelet syndrome and is required for biogenesis of platelet alpha-
AD, editor: Platelets, ed 3, San Diego, 2013, Academic Press, pp 195– granules. Nat Genet 43(8):732–734, 2011.
213. 44. Kahr WH, Hinckley J, Li L, et al: Mutations in NBEAL2, encoding a
19. Pollitt AY, Hughes CE, Watson SP: GPVI and CLEC-2. In Michel- BEACH protein, cause gray platelet syndrome. Nat Genet 43(8):738–740,
son AD, editor: Platelets, ed 3, San Diego, 2013, Academic Press, pp 2011.
215–231. 45. Gissen P, Johnson CA, Morgan NV, et al: Mutations in VPS33B,
20. Madamanchi A, Santoro SA, Zutter MM: alpha2beta1 Integrin. Adv Exp encoding a regulator of SNARE-dependent membrane fusion, cause
Med Biol 819:41–60, 2014. arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome. Nat Genet
21. Watson SP, Farndale RW, Moroi M, et al: Platelet collagen receptors. 36(4):400–404, 2004.
In Marder VJ, Aird WC, Bennett JS, et al, editors: Hemostasis and 46. Maynard DM, Heijnen HF, Horne MK, et al: Proteomic analysis of
thrombosis. Basic principles and clinical practice, ed 6, Philadelphia, 2013, platelet alpha-granules using mass spectrometry. J Thromb Haemost
Lippincott Williams & Wilkins, pp 420–430. 5(9):1945–1955, 2007.
22. Navarro-Nunez L, Langan SA, Nash GB, et al: The physiological 47. Coppinger JA, Cagney G, Toomey S, et al: Characterization of the pro-
and pathophysiological roles of platelet CLEC-2. Thromb Haemost teins released from activated platelets leads to localization of novel plate-
109(6):991–998, 2013. let proteins in human atherosclerotic lesions. Blood 103(6):2096–2104,
23. Bertozzi CC, Schmaier AA, Mericko P, et al: Platelets regulate lym- 2004.
phatic vascular development through CLEC-2-SLP-76 signaling. Blood 48. Blair P, Flaumenhaft R: Platelet alpha-granules: basic biology and clinical
116(4):661–670, 2010. correlates. Blood Rev 23(4):177–189, 2009.
24. Versteeg HH, Heemskerk JW, Levi M, et al: New fundamentals in 49. Italiano JE, Jr, Richardson JL, Patel-Hett S, et al: Angiogenesis is
hemostasis. Physiol Rev 93(1):327–358, 2013. regulated by a novel mechanism: pro- and antiangiogenic proteins are