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140            Part III:  Epochal Hematology                                                                                                                                   Chapter 9:  Hematology in Older Persons             141




                 200. Lugada ES, Mermin J, Kaharuza F, et al: Population-based hematologic and immu-    230. Tofler GH, Massaro J, Levy D, et al: Relation of the prothrombotic state to increasing
                  nologic reference values for a healthy Ugandan population. Clin Diagn Lab Immunol   age (from the Framingham Offspring Study). Am J Cardiol 96(9):1280–1283, 2005.
                  11(1):29–34, 2004.                                    231. Cushman M, Yanez D, Psaty BM, et al: Association of fibrinogen and coagulation
                 201. Nilsson-Ehle H, Jagenburg R, Landahl S, et al: Haematological abnormalities and refer-  factors VII and VIII with cardiovascular risk factors in the elderly: The Cardiovascu-
                  ence intervals in the elderly. A cross-sectional comparative study of three urban Swed-  lar Health Study. Cardiovascular Health Study Investigators. Am J Epidemiol 143(7):
                  ish population samples aged 70, 75 and 81 years. Acta Med Scand 224(6):595–604, 1988.  665–676, 1996.
                 202. Lee SJ, Lindquist K, Segal MR, Covinsky KE: Development and validation of a prognos-    232. Tracy RP, Arnold AM, Ettinger W, et al: The relationship of fibrinogen and factors VII
                  tic index for 4-year mortality in older adults. JAMA 295(7):801–808, 2006.  and VIII to incident cardiovascular disease and death in the elderly: Results from the
                 203. Takubo T, Tatsumi N. [Reference values for hematologic laboratory tests and hemato-  cardiovascular health study. Arterioscler Thromb Vasc Biol 19(7):1776–1783, 1999.
                  logic disorders in the aged] [in Japanese]. Rinsho Byori 48(3):207–216, 2000.    233. Cohen HJ, Harris T, Pieper CF: Coagulation and activation of inflammatory path-
                 204. Haverkate F, Thompson SG, Duckert F: Haemostasis factors in angina pectoris; relation   ways in the development of functional decline and mortality in the elderly. Am J Med
                  to gender, age and acute-phase reaction. Results of the ECAT Angina Pectoris Study   114(3):180–187, 2003.
                  Group. Thromb Haemost 73(4):561–567, 1995.            234. McDermott MM, Greenland P, Green D, et al: D-dimer, inflammatory markers, and
                 205. Kario  K,  Matsuo  T,  Kobayashi  H:  Close  relationship  between  hemostatic  factors   lower extremity functioning in patients with and without peripheral arterial disease.
                  and acute-phase reaction as normal aging process. J Am Geriatr Soc 44(5):614–615,     Circulation 107(25):3191–3198, 2003.
                  1996.                                                 235. Wilson CJ, Cohen HJ, Pieper CF: Cross-linked fibrin degradation products (D-dimer),
                 206. Mari D, Mannucci PM, Coppola R, et al: Hypercoagulability in centenarians: The para-  plasma cytokines, and cognitive decline in community-dwelling elderly persons. J Am
                  dox of successful aging. Blood 85(11):3144–3149, 1995.  Geriatr Soc 51(10):1374–1381, 2003.
                 207. Scarabin PY, Van Dreden P, Bonithon-Kop C, et al: Age-related changes in factor VII     236. Rafnsson SB, Deary IJ, Smith FB, et al: Cognitive decline and markers of inflammation
                  activation in healthy women. Clin Sci (Lond) 75(4):341–343, 1988.  and hemostasis: The Edinburgh Artery Study. J Am Geriatr Soc 55(5):700–707, 2007.
                 208. Balleisen L, Bailey J, Epping PH, et al: Epidemiological study on factor VII, factor     237. McDermott MM, Ferrucci L, Liu K, et al: D-dimer and inflammatory markers as pre-
                  VIII and fibrinogen in an industrial population: I. Baseline data on the relation to age,   dictors of functional decline in men and women with and without peripheral arterial
                  gender, body-weight, smoking, alcohol, pill-using, and menopause. Thromb Haemost   disease. J Am Geriatr Soc 53(10):1688–1696, 2005.
                  54(2):475–479, 1985.                                  238. Yamamoto K, Shimokawa T, Yi H, et al: Aging and obesity augment the stress-induced
                 209. Conlan MG, Folsom AR, Finch A, et al: Associations of factor VIII and von Willebrand   expression of tissue factor gene in the mouse. Blood 100(12):4011–4018, 2002.
                  factor with age, race, sex, and risk factors for atherosclerosis. The Atherosclerosis Risk     239. Kop WJ, Gottdiener JS, Tangen CM, et al: Inflammation and coagulation factors in per-
                  in Communities (ARIC) Study. Thromb Haemost 70(3):380–385, 1993.  sons > 65 years of age with symptoms of depression but without evidence of myocardial
                 210. Ernst E, Resch KL: Fibrinogen as a cardiovascular risk factor: A meta-analysis and   ischemia. Am J Cardiol 89(4):419–424, 2002.
                  review of the literature. Ann Intern Med 118(12):956–963, 1993.    240. Panagiotakos DB, Pitsavos C, Chrysohoou C, et al: Inflammation, coagulation, and
                 211. Cadroy Y, Daviaud P, Saivin S, et al: Distribution of 16 hemostatic laboratory variables   depressive symptomatology in cardiovascular disease-free people; the ATTICA study.
                  assayed in 100 blood donors. Nouv Rev Fr Hematol 32(4):259–264, 1990.  Eur Heart J 25(6):492–499, 2004.
                 212. Gudnason T, Hrafnkelsdottir T, Wall U, et al: Fibrinolytic capacity increases with age     241. von Kanel R, Dimsdale JE, Mills PJ, et al: Effect of Alzheimer caregiving stress and age
                  in healthy humans, while endothelium-dependent vasodilation is unaffected. Thromb   on frailty markers interleukin-6, C-reactive protein, and D-dimer. J Gerontol A Biol Sci
                  Haemost 89(2):374–381, 2003.                           Med Sci 61(9):963–969, 2006.
                 213. Sundell IB, Nilsson TK, Ranby M, et al: Fibrinolytic variables are related to age, sex,     242. von Kanel R, Mills PJ, Fainman C, Dimsdale JE: Effects of psychological stress and
                  blood pressure, and body build measurements: A cross-sectional study in Norsjo,    psychiatric disorders on blood coagulation and fibrinolysis: A biobehavioral pathway
                  Sweden. J Clin Epidemiol 42(8):719–723, 1989.          to coronary artery disease? Psychosom Med 63(4):531–544, 2001.
                 214. Dolan G, Neal K, Cooper P, et al: Protein C, antithrombin III and plasminogen: Effect     243. Walston J, McBurnie MA, Newman A, et al: Frailty and activation of the inflammation
                  of age, sex and blood group. Br J Haematol 86(4):798–803, 1994.  and coagulation systems with and without clinical comorbidities: Results from the Car-
                 215. Pieper CF, Rao KM, Currie MS, et al: Age, functional status, and racial differences in   diovascular Health Study. Arch Intern Med 162(20):2333–2341, 2002.
                  plasma D-dimer levels in community-dwelling elderly persons. J Gerontol A Biol Sci     244. Folsom AR, Boland LL, Cushman M, et al: Frailty and risk of venous thromboembolism
                  Med Sci 55(11):M649–M657, 2000.                        in older adults. J Gerontol A Biol Sci Med Sci 62(1):79–82, 2007.
                 216. Juhan-Vague I, Renucci JF, Grimaux M, et al: Thrombin-activatable fibrinolysis     245. Chinn IK, Blackburn CC, Manley NR, Sempowski GD: Changes in primary lymphoid
                  inhibitor antigen levels and cardiovascular risk factors. Arterioscler Thromb Vasc Biol   organs with aging. Semin Immunol 24(5):309–320, 2012.
                  20(9):2156–2161, 2000.                                246. Aspinall R: Longevity and the immune response. Biogerontology 1(3):273–278, 2000.
                 217. Schatteman KA, Goossens FJ, Scharpe SS, et al: Assay of procarboxypeptidase U, a novel     247. Tyan ML: Age-related decrease in mouse T cell progenitors. J Immunol 118(3):846–851,
                  determinant of the fibrinolytic cascade, in human plasma. Clin Chem 45(6 Pt 1):807–813,   1977.
                  1999.                                                 248. Aspinall R: Age-associated thymic atrophy in the mouse is due to a deficiency affect-
                 218. Mehta J, Mehta P, Lawson D, Saldeen T: Plasma tissue plasminogen activator inhibitor   ing  rearrangement  of  the TCR during  intrathymic  T cell development.  J Immunol
                  levels in coronary artery disease: Correlation with age and serum triglyceride concen-  158(7):3037–3045, 1997.
                  trations. J Am Coll Cardiol 9(2):263–268, 1987.       249. Lacorazza HD, Guevara Patino JA, Weksler ME, et al: Failure of rearranged TCR trans-
                 219. Eliasson M, Evrin PE, Lundblad D: Fibrinogen and fibrinolytic variables in relation to   genes to prevent age-associated thymic involution. J Immunol 163(8):4262–4268, 1999.
                  anthropometry, lipids and blood pressure. The Northern Sweden Monica study. J Clin     250. Hartwig M, Steinmann G: On a causal mechanism of chronic thymic involution in
                  Epidemiol 47(5):513–524, 1994.                         man. Mech Ageing Dev 75(2):151–156, 1994.
                 220. Cawkwell RD: Patient’s age and the activated partial thromboplastin time test. Thromb     251. Plum J, De Smedt M, Leclercq G, et al: Interleukin-7 is a critical growth factor in early
                  Haemost 39(3):780–781, 1978.                           human T-cell development. Blood 88(11):4239–4245, 1996.
                 221. Bauer KA, Weiss LM, Sparrow D, et al: Aging-associated changes in indices of thrombin     252. Le PT, Kurtzberg J, Brandt SJ, et al: Human thymic epithelial cells produce granulocyte
                  generation and protein C activation in humans. Normative Aging Study. J Clin Invest   and macrophage colony-stimulating factors. J Immunol 141(4):1211–1217, 1988.
                  80(6):1527–1534, 1987.                                253. Le PT, Lazorick S, Whichard LP, et al: Human thymic epithelial cells produce IL-6,
                 222. Gurwitz JH, Avorn J, Ross-Degnan D, et al: Aging and the anticoagulant response to   granulocyte-monocyte-CSF, and leukemia inhibitory factor.  J Immunol 145(10):
                  warfarin therapy. Ann Intern Med 116(11):901–904, 1992.  3310–3315, 1990.
                 223. Deguchi K, Deguchi A, Wada H, Murashima S: Study of cardiovascular risk factors and     254. Le PT, Tuck DT, Dinarello CA, et al: Human thymic epithelial cells produce interleukin
                  hemostatic molecular markers in elderly persons. Semin Thromb Hemost 26(1):23–27,   1. J Immunol 138(8):2520–2526, 1987.
                  2000.                                                 255. Gruver AL, Hudson LL, Sempowski GD: Immunosenescence of ageing.  J Pathol
                 224. Scarabin PY, Aillaud MF, Amouyel P, et al: Associations of fibrinogen, factor VII and   211(2):144–156, 2007.
                  PAI-1 with baseline findings among 10,500 male participants in a prospective study of     256. Cakman I, Rohwer J, Schutz RM, et al: Dysregulation between TH1 and TH2 T cell
                  myocardial infarction—the PRIME Study. Prospective Epidemiological Study of Myo-  subpopulations in the elderly. Mech Ageing Dev 87(3):197–209, 1996.
                  cardial Infarction. Thromb Haemost 80(5):749–756, 1998.    257. Hodes RJ: Aging and the immune system. Immunol Rev 160:5–8, 1997.
                 225. Hager K, Platt D: Fibrin degeneration product concentrations (D-dimers) in the course     258. Perussia B, Kobayashi M, Rossi ME, et al: Immune interferon enhances functional
                  of ageing. Gerontology 41(3):159–165, 1995.            properties of human granulocytes: Role of Fc receptors and effect of lymphotoxin,
                 226. Tracy RP, Bovill EG, Fried LP, et al: The distribution of coagulation factors VII and VIII   tumor necrosis factor, and granulocyte-macrophage colony-stimulating factor. J Immu-
                  and fibrinogen in adults over 65 years. Results from the Cardiovascular Health Study.   nol 138(3):765–774, 1987.
                  Ann Epidemiol 2(4):509–519, 1992.                     259. Sokolov VV, Kaplunova OA, Ovseenko TE: [Age factors in architectonics of the splenic
                 227. Laharrague PF, Cambus JP, Fillola G, Corberand JX: Plasma fibrinogen and physiolog-  arterial vessels] [in Russian]. Morfologiia 124(4):57–60, 2003.
                  ical aging. Aging (Milano) 5(6):445–449, 1993.        260. Luscieti P, Hubschmid T, Cottier H, et al: Human lymph node morphology as a func-
                 228. Hager K, Felicetti M, Seefried G, Platt D: Fibrinogen and aging.  Aging (Milano)   tion of age and site. J Clin Pathol 33(5):454–461, 1980.
                  6(2):133–138, 1994.                                   261. Effros RB, Cai Z, Linton PJ: CD8 T cells and aging. Crit Rev Immunol 23(1–2):45–64,
                 229. Takeshita K, Yamamoto K, Ito M, et al: Increased expression of plasminogen activator   2003.
                  inhibitor-1 with fibrin deposition in a murine model of aging, “Klotho” mouse. Semin     262. Globerson A, Effros RB: Ageing of lymphocytes and lymphocytes in the aged. Immunol
                  Thromb Hemost 28(6):545–554, 2002.                     Today 21(10):515–521, 2000.







          Kaushansky_chapter 09_p0129-0142.indd   140                                                                   17/09/15   6:16 pm
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