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2412           Index                                                                                                                                                                                               Index         2413




               CD49f/CD29. See Integrin α β         CD109, 1871                         C/EBPε, 926, 1011
                                    6 1
               CD 50, 1184                          CD110. See Thrombopoietin (TPO) receptor   Cefepime, 384, 385, 387t
               CD51/CD61. See Integrin α β                 (c-mpl, CD110)               Ceftaroline, 384
                                   v 3
               CD 52, 1535                          CD117, 260, 974, 1380t, 1393        Ceftazidime, 384, 385, 387t
               CD 52-targeting antibody. See Alemtuzumab  CD123, 1393                   Ceftobiprole, 385
               CD54. See ICAM-1 (CD54)              CD133, 260                          Celecoxib, 2075, 2121
               CD55, 572, 1053f, 1871               CD135 (Flt3), 309                   Celiac disease, 597, 630, 1575
               CD56 (NCAM), 1142, 1189, 1699, 1726, 1737  CD138 (syndecan 1), 1141, 1712, 1714, 1737  Cell adhesion, 65–68, 67t
               CD56 bright  NK cells, 93, 1189      CD142. See Tissue factor (TF)         BCR-ABL1 and, 1440–1441
               CD57 (LEU7), 1528                    CD143, 1144t                          in sickle cell disease, 764–765
               CD58 (LFA-3), 1184, 1185, 1978       CD144, 68                           Cell cycle
               CD59, 572, 1053f, 1285, 1871, 2358   CD148, 1172                           cancer chemotherapy and, 317
               CD59 blood group, 2333t              CD151, 1871                           regulation, 213–241, 214f
               CD61, 1184                           CD152 (CTLA-4), 424, 1184               checkpoints, 218–219
               CD62E. See E-selectin                CD154. See CD40 ligand (CD40L, CD154)   cyclins and cyclin-dependent kinases,
               CD62L. See L-selectin                CD156a, 1144t                              213–218, 215t, 217f
               CD62L+ cells (memory stem cells), 411  CD156b, 1144t                         histone deacetylases, 239–240, 239t,
               CD62P. See P-selectin                CD157, 1144t                               240f
               CD63, 1009, 1011, 1013, 1836, 1871   CD163, 499, 1061, 1080                  oncogenes, 219–222
               CD64. See Fcγ receptor I (FCγRI, CD64)  CD164, 260                           proteasome, 240–241
               CD65, 1380t, 1383, 1512              CD178, 1564                             tumor-suppressor genes, 237–239
               CD66, 1014                           CD200, 1084                         Cell cycle-active antineoplastic agents,
               CD68, 1013                           CD-209 (DC-SIGN), 308, 1057t, 1082         329–331
               CD69, 948                            CD224, 1144t                        Cell dehydration, in sickle cell disease, 764
               CD70, 1788                           CD244, 949                          Cell fusion, 269
               CD72, 1163                           CD247, 1177                         Cell growth and metabolism
               CD73, 1144t, 1834, 1971, 1972f       CD278 (iCOS), 1184                    gene expression and, 196
               CD79, 1785                           CD279 (PDCD1), 1184                   in hematopoietic stem cells, 196–197, 197f
               CD79a (Ig-α)                         2-CDA. See Cladribine                 homeostasis, 191
                 in Burkitt lymphoma, 1674          CDAN1, 565                            in leukemias, 197–198, 199f
                 in diffuse large B-cell lymphoma, 1627  CDAs. See Congenital dyserythropoietic   in lymphomas, 199–200
                 in extranodal marginal zone lymphoma,     anemias (CDAs)                 in myeloma, 200–201
                       1665                         Cdc42, 309, 1841, 1883                signaling and nutrients, 191–192
                 in follicular lymphoma, 1642       CDDO-Me, 1403                         signal transduction and, 193–196, 194f,
                 immunoglobulin M and, 1162, 1162f  CDK4, 1653                                 195f
                 in precursor B cells, 1168         CDKIs (cyclin-dependent kinase inhibitors),   Cell homing, 68–71
                 in primary mediastinal large B-cell       217–218, 1539                Cell-mediated cytotoxicity, 1190–1191, 1190f
                       lymphoma, 1634               CDKN1B, 234t                        Cell proliferation gene signature, 1654
               CD79B, 233t, 236t                    CDKN2 (p16), 232t, 236t, 1654, 1734  Cell signaling. See Signal transduction
               CD79b (Ig-β), 1162, 1162f, 1168      CDKN2A/B, 177f, 1508                       pathways
               CD80, 1183, 1184, 1185f              CDKN2c, 234t                        Cell-surface proteins, 487
               CD86                                 cdks. See under Cyclin-dependent kinase   Cellular immunity, newborn, 108
                 in dendritic cell maturation, 309         (cdk)                        Cellular senescence, 132
                 in T-cell interactions, 1183, 1184, 1185f  CDRs (complementarity determining   Cellular therapy. See Immune cell therapy
               CD87, 2358                                  region), 1170                       (adoptive cellular therapy)
               CD89, 1008                           CDw32 (FcγRII), 953                 Central nervous system. See also Neurologic
               CD90, 260                            ceAML (clonally evolved acute myelogenous   disease/symptoms
               CD94, 1190                                  leukemia), 1281                leukemia, 1510, 1515, 1516, 1518
               CD95. See Fas (CD95)                 C/EBPA (CEBPA, CEPBα)                 macrophages, 1083
               CD97, 1059                             in acute myelogenous leukemia, 181, 181t,   microglia, 1083
               CD99, 1977t, 1978                           182, 226t, 363, 1378t, 1379    primary lymphoma, 1244f, 1246, 1579
               CD102. See ICAM-2 (CD102)              in myelodysplastic syndromes, 181t, 1345,   Central venous catheter placement, bleeding
               CD106. See Vascular cell adhesion molecule   1351                               risk and, 2384
                       (VCAM)-1                     CEBPB, 1699                         Centromere, 175t
               CD107a (LAMP-1), 1873                C/EBP homologous protein (CHOP), 204f,   CEP. See Congenital erythropoietic porphyria
               CD107b (LAMP-2), 1873                       205, 208f                           (CEP)








          Kaushansky_index_p2393-2506.indd   2412                                                                       9/21/15   3:21 PM
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