Page 2447 - Williams Hematology ( PDFDrive )

2418 Index Index 2419

Colony-forming unit-granulocyte-monocyte Complement system Congenital thrombotic thrombocytopenic
(CFU-GM), 100, 263 deficiencies, 1213t, 1232 purpura (Upshaw-Schulman
in aplastic anemia, 515 in inflammation, 286t, 289–290, 289f syndrome), 2257–2258
Colony-stimulating factor (CSF), 105, Complete cytogenic response (CCyR), 1452t Congestive heart failure, history of, 5
939–940 Complete hematologic response (CHR), Congo red stain, 1773, 1776, 1776f
Colony-stimulating factor (CSF)-1, 1287 1452t Conjugated estrogens, for uremia, 2084
Colton blood group/antigens, 2331t, 2345t Complete molecular response (CMR), 1452t Connective tissue tumors, polycythemia
Combined immunodeficiencies (CID) Computed tomography (CT), in pulmonary with, 879
Ca entry channel defects, 1221 embolism, 2271, 2272f Consciousness, history of impairment of, 5
2+
CD27 deficiency, 1220 Concentrate film, 29 Consensus E-box motifs (CANNTG), 262
clinical features, 1213t Conditional ablation, suicide genes for, 416 Constant region, 1175
coronin-1A deficiency, 1220 Confusion, history of, 5 Constipation, history of, 5
CTPS1 deficiency, 1220–1221 Congenital adrenal hyperplasia, 560 Co phenotype, 2343
null
dedicator of cytokinesis 9 deficiency, Congenital alopecia and absence of thymus, Cooley anemia, 743. See also β-thalassemias
1221–1222 1223 Coombs (direct antiglobulin) test, 823, 833,
defects of T-cell–receptor signaling, 1220 Congenital amegakaryocytic 834t, 2349, 2372
magnesium transporter 1 defects, 1221 thrombocytopenia (CAMT), 530t, COPP-ABVD regimen, for Hodgkin
major histocompatibility complex class I 532, 1822 lymphoma, 1612t, 1614
deficiency, 1221 Congenital disorder of glycosylation II. See Copper, 652t, 811
major histocompatibility complex class II Leukocyte adhesion deficiency type Copper deficiency, 653
deficiency, 1221 2 (LAD-2) neutropenia and, 995
with multiple intestinal atresia, 1222 Congenital dyserythropoietic anemias, 608 sideroblastic anemia and, 919–920
Omenn syndrome, 1166, 1219–1220 Congenital dyserythropoietic anemias COPP regimen
severe. See Severe combined (CDAs), 563–569 for diffuse large B-cell lymphoma,
immunodeficiency (SCID) atypical, 568, 568t 1628–1629
T-cell immunodeficiencies with impaired definition and history, 563 for Hodgkin lymphoma, 1612t
NF-κB activation, 1220 differential diagnosis, 563, 564f, 568–569, Coproporphyrinogen oxidase (CPO), 895
with venoocclusive disease, 1222 637 Coproporphyrinogens, 891f, 891t, 893f
Combined system disease, 602, 602f epidemiology, 563–564 Copy-number neutral LOH, 174, 177f
COMMD7, 1853 type I Copy number variants (CNVs), 147
Common lymphoid progenitor (CLP), clinical features, 564–565, 566f Cord blood, 102, 357, 358
269–270, 1151 genetics, 565–566 Cord colitis, 357
Common myeloid progenitor (CMP), laboratory features, 565, 565f Cordocentesis, 854
270–271, 1151 therapy, course, and prognosis, 566 Coronary artery bypass grafting, 2296
Common variable immunodeficiency type II Coronary artery disease, 1850, 2240. See also
(CVID), 993, 1214t, 1216, 1575t clinical and laboratory features, Cardiovascular disease
Compartment syndrome, 2118 566–567 Coronary stents, 2293
Compatibility testing, 2349–2350, 2350t genetics, 567 Coronin-1A deficiency, 1220
Competitive repopulation, 259 therapy, course, and prognosis, 567–568 Cor pulmonale, 882
Complement type III, 568 Corrected count increment (CCI), 2385,
in antiphospholipid syndrome, 2237 Congenital erythropoietic porphyria (CEP), 2387–2388
defects, in atypical hemolytic uremic 889, 896–897 Corrinoids, 588
syndrome, 2259–2260, 2259t clinical features, 890t, 896f, 897 Corrin ring, 588, 588f, 589f
in paroxysmal nocturnal hemoglobinuria, definition and history, 890, 896 Corynebacterium diphtheriae pharyngitis, 1268
572, 573f diagnosis, 897 Cost antigens, 2333t
Complementarity determining region enzymes affected by, 890t Cough, history of, 5
(CDRs), 1170 laboratory features, 891t Coumadin. See Warfarin
Complementary DNA (cDNA) pathogenesis of clinical findings, 897 Coumarin, 393
in Fanconi anemia, 530 pathophysiology, 896 Cow’s milk anemia, 630
libraries, 421 therapy, 897 COX. See under Cyclooxygenase (COX)
von Willebrand factor, 2164 Congenital Heinz body hemolytic anemia, CPB2, 1935–1936
Complement (C3)-coated red cells, 499 781–782 Cpg islands, 168
Complement fixation, 829 Congenital immunodeficiency diseases. See CPO, 905
Complement receptor 1, 815, 1054 Immunodeficiency diseases CPO (coproporphyrinogen oxidase), 895
Complement receptor 3. See CD11b Congenital leukemia, 1386 CPX-351, for myelodysplastic syndromes,
Complement receptors, 1053f, 1054 Congenital neutropenia, 992–993, 993f 1361

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