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2446 Index Index 2447
Hodgkin lymphoma, HIV-associated (Cont.): HPFH. See Hereditary persistence of fetal hematopoietic cell transplantation for,
hematopoietic cell transplantation for, hemoglobin (HPFH) 1248
1248 HPP. See Hereditary pyropoikilocytosis hemophagocytic syndrome, 1250–1251,
incidence, 1243, 1247, 1605 (HPP) 1250t
laboratory features, 1610 HPRT (hypoxanthine Hodgkin lymphoma. See Hodgkin
histopathology, 1497t, 1599–1601, phosphoribosyltransferase), 1439 lymphoma, HIV-associated
1600f, 1601f HPS (Hermansky-Pudlak syndrome). See incidence, 1243, 1244f, 1571
monocytosis, 1097 Hermansky-Pudlak syndrome Kaposi sarcoma–associated
radiographic, 1608, 1608f (HPS) herpesvirus-associated
nodular lymphocyte-predominant HR (homologous recombination), 453 inflammatory cytokine syndrome,
differential diagnosis, 1609 HRE (hypoxia-response element), 484, 486 1250
immunophenotype, 1497t, 1604t HS. See Hereditary spherocytosis (HS) plasmablastic lymphoma, 1246
laboratory features, 1497t, 1600–1601, HS40, 730 primary central nervous system
1600f, 1601f, 1609 HSCs. See Hematopoietic stem cells (HSCs) lymphoma, 1244f, 1246, 1579
treatment, 1616 HSCT. See Hematopoietic cell transplantation primary effusion lymphoma, 1246–1247,
in pregnancy, 123–124 (HCT) 1496t
staging, 1609–1610, 1610t HSP (Henoch-Schönlein purpura), 1162, prognosis, 1247
therapy, 1610–1616 2103–2104, 2103f Human immunodeficiency virus (HIV)
advanced disease, 1613–1615 Hsp90, 219, 487 infection
chemotherapy regimens, 1612t HSTCL (hepatosplenic T-cell lymphoma), anemia in
clinical trials, 1615t 185t, 1498t, 1567, 1701 causes, 1251–1252, 1251t
complications, 1617–1618 HSV. See under Herpes simplex virus (HSV) incidence, 1251
favorable, limited-stage disease, HSV-TK (herpes simplex virus thymidine medication-related, 1252
1611–1613, 1612t kinase), 440 treatment, 1252
hematopoietic cell transplantation, HTLV. See Human T lymphotropic virus antiphospholipid antibodies and, 2234,
366 (human T-cell leukemia/lymphoma 2241
historical perspective, 1610–1611 virus) (HTLV)-1 aplastic anemia in, 518
nodular lymphocyte predominant HtrA2, 208 cardiovascular disease and, 2281
disease, 1616 huCRIg(L), 1053f CCR5 expression in, 440, 1240
recurrent disease, 1616 huCRIg(S), 1053f clinical features, 1240–1242
unfavorable limited-stage disease, 1613 Human androgen-receptor gene as complication of factor VIII replacement,
Holotranscobalamin, 593, 603 (HUMARA), 883 2126
Holotransferrin, 622, 623f Human Genome Project, 152 disease progression, 1240–1242
Homocysteine, 598–599, 603, 1976, 2222 Human herpes virus (HHV)-6 epidemiology and transmission,
Homocystinuria (cbIE and cbIG), 607, 607t, aplastic anemia and, 518 1239–1240
2222 mononucleosis syndrome and, 1268 lymphocytopenia in, 1204
Homogenous nucleation, 763 T-cell therapy, 412 malignancies in. See Human
Homologous desensitization, 1877 Human herpes virus (HHV)-8 immunodeficiency virus
Homologous recombination (HR), 453 in Castleman disease, 1249–1250, 1496t (HIV)–associated malignancies
Horn cells. See Keratocytes (horn cells) epidemiology, 1573–1574 mannose-binding lectin deficiency and,
Host defense in Kaposi sarcoma, 1573 1017
basophils and mast cells in, 969–970 in primary effusion lymphoma, mast cells in, 970, 972
iron deficiency and, 631–632 1246–1247, 1574 megaloblastic anemia in, 605
Howell-Jolly bodies Human immunodeficiency virus (HIV)-1, mononucleosis syndrome in, 1268
characteristics, 467–468, 467f 1239 neutropenia in, 997, 1254
in hyposplenism, 868–869, 869f Human immunodeficiency virus (HIV)-2, opportunistic infections in, 1240–1241,
in megaloblastic anemia, 594 1239 1241t
HOX11, 863, 1508t, 1513t Human immunodeficiency virus pathogenesis, 1240
HOX11L2, 1508t (HIV)–associated malignancies, persistent B19 parvovirus infection with
HOXA9, 234t, 266, 268 1500t red cell aplasia in, 543, 544, 545f,
HOXB4, 266, 268 Burkitt lymphoma, 187, 1244f, 1245, 1247, 1251–1252
Hox family of transcription factors, 262 1672, 1676 porphyria cutanea tarda in, 906–907
Hoyeraal-Hreidarsson syndrome, 531 Castleman disease, 1249–1250 in pregnancy, 1269
HPAs. See Human platelet antigens (HPAs) diffuse large B-cell lymphoma, 187, prevention and cure, 1242–1243
5-HPETE, 289 1243–1245, 1244f, 1247, 1571 primary, 1240, 1268
12-HPETE, 1877 etiology, 1573 staging, 1240–1241, 1240t
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