Page 2495 - Williams Hematology ( PDFDrive )

2466 Index Index 2467

Mitoxantrone (Cont.): MOMA-1, 1082f clinical manifestations, 1091
adverse effects, 328 MOMP (mitochondrial outer membrane histiocytosis, 1090–1091, 1090t. See also
for chronic lymphocytic leukemia, 1535 permeabilization), 206 Histiocytosis(es)
for diffuse large B-cell lymphoma, 1631 MondoA, 197 monocytopenia. See Monocytopenia
for follicular lymphoma, 1645t Monge disease, 875 monocytosis. See Monocytosis
secondary acute myelogenous leukemia Monoblasts, 1046 qualitative, 1091
and, 1407 Monoclonal antibodies (mAbs), 343–346. thromboatherogenesis and, 1092
Mixed chimerism, following See also specific drugs distribution
reduced-intensity transplantation, dose and toxicity, 343t in marrow, 32t, 34, 1081–1082
360–361 for follicular lymphoma, 1645–1646 in nonlymphohematopoietic organs,
Mixed leukemia, 1386 immunotoxins, 345–346 1082–1083
Mixed-lineage kinase domain-like (MLKL) for mycosis fungoides, 1687 functions
protein, 207 for myeloma, 345, 345f, 346t, 1755 cellular interactions, 1066, 1071, 1071f
Mixed-lineage leukemia (MLL) protein, 169 radioimmunoconjugates, 346, 360 G-protein-coupled receptors and, 1060t
MLASA (mitochondrial myopathy and Monoclonal antibody-specific inflammasome, 1063–1064, 1065f,
sideroblastic anemia), 919 immobilization of platelet antigens 1066f
MLKp1, 568 (MAPIPA) assay, 2000 interaction with coagulation cascade,
MLL, 170 Monoclonal B-cell lymphocytosis (MBL), 1059
in acute lymphoblastic leukemia, 1508, 1199–1200, 1201t, 1542–1543 motility, 1059, 1060t
1512, 1521 Monoclonal gammopathy of unknown heterogeneity, 1078–1081, 1079f, 1080t
in acute myelogenous leukemia, 215, 225, significance (MGUS), 1721. histochemistry, 1048, 1049t
1376, 1383, 1384t See also Essential monoclonal inflammatory response in, 1970f
in follicular lymphoma, 235t gammopathy markers, 1080t
in mantle cell lymphoma, 236t Monoclonal gammopathy with a coinciding in myelodysplastic syndromes, 1353
in myeloma, 234t disease, 1724–1725, 1725t in newborn, 105t
MLL2 (KMT2D), 236t, 1644 Monoclonal immunoglobulin deposition normal blood concentration, 1095
MLL3, 1347 disease (MIDD), 1497t, 1744 precursors, 1046
MLL-AF4 (KMTA/AFF1), 1507, 1513t Monoclonal mast cell activation syndrome properties, 1095
MLL-ENL, 1508t (MMAS), 977–978 receptors
MLL (mixed-lineage leukemia) protein, 169 Monoclonal proteins. See M-proteins CD4, 1056–1057
MLL-PTD, 226t, 1378, 1378t Monocyte chemoattractant protein CD11, 1056
MMACHC, 2263 (MCP-1). See CCL2 (monocyte CD14, 1056
MMAS (monoclonal mast cell activation chemoattractant protein, MCP-1) CD16, 1056
syndrome), 977–978 Monocyte colony-stimulating factor chemokine, 1057–1058, 1058t
MML (myelomastocytic leukemia), 978 (M-CSF), 264t, 1352 complement, 1054
MMPs (matrix metalloproteinases), 1014, Monocyte–macrophage system, 619 Fc, 1053–1054, 1053f
1874, 1881, 2307, 2311 Monocytes human leukocyte antigen class II,
MMR (major molecular response), activation, 283 1055–1056
1452t classical and alternative, 1085–1086, non–toll-like, nonopsonic, 1054–1055,
MMSET (WHSC1), 236t, 1735 1086f 1056f, 1057t
MNP (marginal neutrophil pool), 942t immunomodulation, 1084, 1085f surface, 1052–1053, 1058t
MNS blood group/antigens, 2331t, 2334t, innate, 1084–1085 surface antigens, 1052f
2339, 2343, 2344t in response to inflammation and toll-like, 1054, 1055f
Mo1. See CD11b/CD18 (Mac-1, Mo1, CR3, tumors, 1083–1084, 1084f reference ranges, 18t
α β ) blood dendritic cells and, 1092 release, 72
M 2
Mocetinostat, 240 cell adhesion and homing, 66 in sickle cell disease, 765
Model of end-stage liver disease (MELD), in children, 15t small immature, 1045
2192 cytochemical reactions, 1049t structure, 20f, 23, 1045–1047, 1046–1047,
Moderate-deviation clonal myeloid disorders, development, 1075–1076 1046f, 1047f, 1048f, 1049f
1276t, 1278–1279 growth, differentiation, and turnover, subset variations in disease, 1098
Moderately severe-deviation clonal myeloid 1076, 1076f Monocytic leukemia
disorders, 1276t, 1279 maturation and differentiation, acute. See Acute monocytic leukemia
Moesin, 1006 1077–1078, 1077f, chronic. See Chronic myelomonocytic
Mogamulizumab, for adult T-cell leukemia/ 1078f leukemia
lymphoma, 1701 disorders Monocytic progenitors, 271
Molecular biology, 152–153 classification, 1089, 1090t Monocytoid B cells, 1595

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