Page 2494 - Williams Hematology ( PDFDrive )

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2464 Index Index 2465

for acute lymphoblastic leukemia, 1515, MGA1 (autosomal recessive megaloblastic Migraines, 2239
1516, 1517 anemia), 605 Milatuzumab, for myeloma, 346t
adverse effects, 321, 368, 599, 1407, 1519t MGC22455. See TSSC6 Milk, folate-binding proteins of, 588
for α-heavy-chain disease, 1809 MGCD0103, 1403 Milk fat globulin, macrophages and, 1054
for Burkitt lymphoma, 1675, 1675t, 1676 MGMT (O -methylguanine-DNA Miller-Fisher syndrome, 1790
6
for diffuse large B-cell lymphoma, 1628 methyltransferase), 442 Minimal-deviation myeloid clonal disorders,
for graft-versus-host disease prophylaxis, MGUS (monoclonal gammopathy of 1276t, 1277–1278
368, 371 unknown significance), 1721. Minimal residual disease (MRD)
for intravascular large B-cell lymphoma, See also Essential monoclonal in acute myelogenous leukemia, 1412,
1636 gammopathy 1414
for Langerhans cell histiocytosis, 1106, mHAgs (minor histocompatibility antigens), in chronic lymphocytic leukemia, 1540
1107 413–414 in chronic myelogenous leukemia,
for large granular lymphocytic leukemia, MHC. See under Major histocompatibility 1463–1464
1567 complex (MHC) in hairy cell leukemia, 1554, 1558
leucovorin rescue for, 320–321 MI. See Myocardial infarction (MI) in myeloma, 1716–1717, 1758
for lymphomatoid papulosis, 1689 MIC3. See CD9 next-generation sequencing for detection
mechanism of action, 318–319, 320f Micafungin, 388t, 389 of, 163
megaloblastic anemia and, 605, 606t Miconazole, 2078 Minor-BCR-breakpoint-positive chronic
for mycosis fungoides, 1687 Microangiopathic hemolytic anemia, myelogenous leukemia, 1449
pharmacology, 319–321 803–804, 803t Minor cytogenic response (mCyR), 1452t
resistance to, 319t Microarray analysis, 174–175, 177f Minor histocompatibility antigens (mHAgs),
structure, 320f Micrococcus infection, 2340 413–414
6-Methoxy-arabinosylguanine. See Microcyte, 21 MIP (macrophage inflammatory protein)-1α,
Nelarabine Microcytic hypochromic anemia, 506 288t, 1440, 1737–1738, 1738f,
Methoxypsoralen, for mastocytosis, 977 Microglia, 1083 1739f
Methylcobalamin, 589, 592 β -Microglobulin MIRL (membrane inhibitor of reactive lysis),
2
α-Methyldopa, 827, 831, 832, 835, 840 in chronic lymphocytic leukemia, 1532 572
Methylene blue, 793 in diffuse large B-cell lymphoma, 1632 miRNAs. See MicroRNAs
Methylenetetrahydrofolate reductase in essential monoclonal gammopathy, 1726 Missense mutations, 146
(MTHFR). See under MTHFR in human leukocyte antigen, 2353 Mithramycin, 2079
Methylfolate trap hypothesis, 590–591, 590f infection susceptibility and, 1746 Mitochondria
Methylmalonic acid, 603 in iron homeostasis, 621t in cell death pathways, 205
Methylmalonic aciduria (cblA, cblB, cblH), in mantle cell lymphoma, 1655 ferritin in, 624
607, 607t in myeloma, 1715–1716, 1746, 1747–1748, iron in, 623–624
Methylmalonic aciduria and homocystinuria 1748t, 1759 in platelets, 1840
(cblC, cblD, cblF), 607, 607t Microgranular leukemia, 1390 Mitochondrial antiviral signaling protein
Methylmalonyl coenzyme A mutase, 589, Microparticles, platelet, 1854 (MAVS), 302, 302f, 303
589f MicroRNAs Mitochondrial myopathy and sideroblastic
Methylprednisolone. See also ESHAP in acute myelogenous leukemia, 1280 anemia (MLASA), 919
regimen in chronic lymphocytic leukemia, 1529, Mitochondrial outer membrane
for autoimmune hemolytic anemia, 838 1532 permeabilization (MOMP), 206
for chronic lymphocytic leukemia, in erythropoiesis, 487–488 Mitogen-activated extracellular-regulated
1536–1537 in gene regulation, 239 kinase (MEK), 298, 1016
for Diamond-Blackfan anemia, 540 in myelodysplastic syndromes, 1347 Mitogen-activated protein kinase (MAPK),
for diffuse alveolar hemorrhage, 368 in neutrophil granule protein expression, 237, 266, 1054, 1055f, 1178., 1817
for graft-versus-host disease, 371 1011 Mitogen-activated protein kinase (MAPK)
for immune thrombocytopenia, 2004 platelet, 1853 pathway, 237, 252
5
N -Methyltetrahydrofolate–homocysteine Microvilli, neutrophil, 1006 Mitogens, 1139
methyltransferase, 585, 587f, 589 MIDAS (metal ion-dependent adhesion site), Mitomycin C, 1824, 2262–2263
5
N -Methyltetrahydrofolate–homocysteine 2044–2045, 2044f Mitosis, 213
methyltransferase deficiency, 608 Midazolam, 28 Mitoxantrone, 327–328
Methylthioadenosine phosphorylase MIDD (monoclonal immunoglobulin for acute lymphoblastic leukemia, 1516
(MTAP), 238–239 deposition disease), 1497t, 1744 for acute myelogenous leukemia, 1395,
Metoclopramide, 901 Midostaurin, 977, 1403 1395t, 1402t
Mevalonate kinase deficiency, 568 Migfilin, 1832t, 1837 in children, 1409
MF. See Mycosis fungoides (MF) Miglustat, 1128, 1130 in older patients, 1408

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